Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EDNRB | P24530 | 1/20 | 0.34 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.33 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.32 |
| ▸ | CMA1 | P23946 | 4/20 | 0.31 |
| ▸ | FEN1 | P39748 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.31 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.31 |
| ▸ | FABP3 | P05413 | 1/20 | 0.31 |
| ▸ | FABP4 | P15090 | 1/20 | 0.31 |
| ▸ | FABP5 | Q01469 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7572056 | 0.87 | PTGDR2 (0.41) | EDNRBPTGDR2KDM5BCMA1FEN1 | |
| SCHEMBL7571920 | 0.76 | HDAC6 (0.41) | EDNRBPTGDR2 | |
| SCHEMBL8923924 | 0.70 | HDAC6 (0.40) | PTGDR2 | |
| SCHEMBL7574883 | 0.70 | PTGDR2 (0.40) | EDNRBPTGDR2 | |
| SCHEMBL10673575 | 0.58 | MAPK8 (0.54) | — | |
| SCHEMBL26747851 | 0.56 | APAF1 (0.52) | — | |
| SCHEMBL7654816 | 0.56 | PGR (0.55) | — | |
| SCHEMBL25920056 | 0.55 | ACVR1 (0.44) | — | |
| SCHEMBL80194 | 0.55 | USP5 (0.68) | THRB | |
| SCHEMBL311956 | 0.55 | USP5 (0.68) | THRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5654309-A | KIDNEY, CARDIOVASCULAR AND RESPIRATORY SYSTEM DISORDERS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-08-05 | — | — | US | claimed |