Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 5/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 3/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8924428 | 0.70 | PPARA (0.42) | PPARGEPHX2PPARDTSHR | |
| SCHEMBL8768939 | 0.70 | PPARA (0.45) | PPARGHDAC1HDAC6PPARDTSHR | |
| SCHEMBL8925673 | 0.66 | HDAC1 (0.44) | PPARGACHEHDAC1HDAC6PPARD | |
| SCHEMBL8767697 | 0.63 | PPARG (0.46) | PPARGHDAC1HDAC6PPARDHDAC3 | |
| SCHEMBL2539350 | 0.61 | L3MBTL1 (0.53) | RAB9AL3MBTL1 | |
| SCHEMBL8768870 | 0.61 | PPARA (0.44) | PPARGEPHX2HDAC1HDAC6PPARD | |
| SCHEMBL6001907 | 0.61 | PTPRC (0.50) | ALDH1A1RAB9AL3MBTL1 | |
| SCHEMBL27701493 | 0.60 | PTGER1 (0.44) | PPARGHDAC6PPARDTSHRALDH1A1 | |
| SCHEMBL5305401 | 0.60 | LMNA (0.60) | PLA2G1BATG4BALDH1A1TP53RAB9A | |
| SCHEMBL9170209 | 0.60 | EPHX2 (0.50) | PPARGEPHX2TSHRALDH1A1TP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5658944-A | ANTICHOLESTEROL AGENTS | THE UNIVERSITY OF SOUTH CAROLINA (US) | 1997-08-19 | — | — | US | disclosed |