SCHEMBL8928107

SCHEMBL8928107

COc1ccc(N(c2ccc(-c3ccc(N(c4ccc(OC)cc4)c4ccc5c(c4)c4ccccc4n5-c4ccccc4)cc3)cc2)c2ccc3c(c2)c2ccccc2n3-c2ccccc2)cc1

nearest known ligand 0.47

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSPO P30536 4/20 0.47
KDM4E B2RXH2 4/20 0.46
MAPT P10636 4/20 0.46
L3MBTL1 Q9Y468 3/20 0.46
ALDH1A1 P00352 3/20 0.46
HTT P42858 2/20 0.46
MEN1 O00255 2/20 0.46
HPGD P15428 2/20 0.46
KMT2A Q03164 2/20 0.46
HSD17B10 Q99714 1/20 0.46
ATM Q13315 1/20 0.45
EDNRA P25101 3/20 0.43
KDR P35968 1/20 0.43
OXTR P30559 1/20 0.40
GRIK2 Q13002 1/20 0.40
LMNA P02545 1/20 0.40
TP53 P04637 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8928207 1.00 TSPO (0.47) TSPOKDM4EMAPTL3MBTL1ALDH1A1
SCHEMBL16865323 0.99 TSPO (0.47) TSPOKDM4EMAPTL3MBTL1ALDH1A1
SCHEMBL8928202 0.96 MAPT (0.49) TSPOKDM4EMAPTL3MBTL1ALDH1A1
SCHEMBL8928090 0.96 MAPT (0.49) TSPOKDM4EMAPTL3MBTL1ALDH1A1
SCHEMBL8928272 0.96 MAPT (0.49) TSPOKDM4EMAPTL3MBTL1ALDH1A1
SCHEMBL10025011 0.96 KDM4E (0.48) TSPOKDM4EMAPTL3MBTL1ALDH1A1
SCHEMBL12057422 0.95 TSPO (0.53) TSPOKDM4EMAPTL3MBTL1ALDH1A1
SCHEMBL12299178 0.95 MAPT (0.48) TSPOKDM4EMAPTL3MBTL1ALDH1A1
SCHEMBL15306453 0.93 TSPO (0.51) TSPOKDM4EMAPTL3MBTL1ALDH1A1
SCHEMBL12721657 0.92 TSPO (0.42) TSPOKDM4EMAPTL3MBTL1ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240244963-A1 PHENYLCARBAZOLE-BASED COMPOUNDS AND FLUORENE-BASED COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICE AND FLAT PANEL DISPLAY DEVICE COMPRISING THE SAME SAMSUNG DISPLAY CO LTD (KR) 2024-07-18 US disclosed
US-20240244963-A1 PHENYLCARBAZOLE-BASED COMPOUNDS AND FLUORENE-BASED COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICE AND FLAT PANEL DISPLAY DEVICE COMPRISING THE SAME SAMSUNG DISPLAY CO LTD (KR) 2024-07-18 US disclosed
US-11844229-B2 Electroluminescent element, and light emitting device, display device and lighting device each using organic electroluminescent element UDC IRELAND LIMITED (IE) 2023-12-12 US disclosed
US-11700769-B2 Organic electroluminescent element, compound, and light emitting device, display device and lighting system, using said element UDC IRELAND LIMITED (IE) 2023-07-11 US disclosed
US-20230120805-A1 PHENYLCARBAZOLE-BASED COMPOUNDS AND FLUORENE-BASED COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICE AND FLAT PANEL DISPLAY DEVICE COMPRISING THE SAME SAMSUNG DISPLAY CO LTD (KR) 2023-04-20 US disclosed
US-11563178-B2 Organic electroluminescent element, compound for use in the element, and light emitting device, display device, and illumination device using the element UDC IRELAND LIMITED (IE) 2023-01-24 US disclosed
US-20200203648-A1 Electroluminescent Element, And Light Emitting Device, Display Device And Lighting Device Each Using Organic Electroluminescent Element UDC IRELAND LIMITED (IE) 2020-06-25 US disclosed
US-20200152884-A1 PHENYLCARBAZOLE-BASED COMPOUNDS AND FLUORENE-BASED COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICE AND FLAT PANEL DISPLAY DEVICE COMPRISING THE SAME SAMSUNG DISPLAY CO LTD (KR) 2020-05-14 US disclosed
US-10573821-B2 Phenylcarbazole-based compounds and fluorene-based compounds and organic light emitting device and flat panel display device comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2020-02-25 US disclosed
US-20200058883-A1 ORGANIC ELECTRIC LIGHT EMITTING ELEMENT, MATERIAL FOR SAID ELEMENT, AND LIGHT EMITTING DEVICE, DISPLAY DEVICE, AND ILLUMINATION DEVICE EMPLOYING SAID ELEMENT UDC IRELAND LTD (IE) 2020-02-20 US disclosed
US-8188315-B2 OLED/organic light emitters using a compound of 9,9-dimethylfluorenes anda ring such as carbazole for electrical stabity; glass transition temperature; crystal growth inhibiters; low voltage; current density; industrial scale; charge transfer/generating compounds; color dopes SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2012-05-29 US disclosed
US-8021764-B2 Phenylcarbazole-based compound and organic electroluminescent device employing the same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2011-09-20 US disclosed
US-8021764-B2 Phenylcarbazole-based compound and organic electroluminescent device employing the same SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2011-09-20 US disclosed
US-8021765-B2 synthesized by reacting a carbazole derivative with an aromatic diamines; electric stability, superior charge transport ability, and high glass transition temperature; suitable for fluorescent and phosphorescent devices having all colors, including red, green, blue, and white colors SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2011-09-20 US disclosed
US-8021765-B2 synthesized by reacting a carbazole derivative with an aromatic diamines; electric stability, superior charge transport ability, and high glass transition temperature; suitable for fluorescent and phosphorescent devices having all colors, including red, green, blue, and white colors SAMSUNG MOBILE DISPLAY CO., LTD. (KR) 2011-09-20 US disclosed
US-20080107919-A1 Phenylcarbazole-based compound and organic electroluminescent device employing the same SAMSUNG DISPLAY CO., LTD. (KR) 2008-05-08 US disclosed
US-20080107919-A1 Phenylcarbazole-based compound and organic electroluminescent device employing the same SAMSUNG DISPLAY CO., LTD. (KR) 2008-05-08 US disclosed
EP-1862524-A1 Organic light emitting device and flat panel display device comprising the same Samsung SDI Co., Ltd. (KR) 2007-12-05 EP disclosed
US-20070231503-A1 Organic light emitting device and flat panel display device comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2007-10-04 US disclosed
US-20070231503-A1 Organic light emitting device and flat panel display device comprising the same SAMSUNG DISPLAY CO., LTD. (KR) 2007-10-04 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200152884-A1 PHENYLCARBAZOLE-BASED COMPOUNDS AND FLUORENE-BASED COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICE AND FLAT PANEL DISPLAY DEVICE COMPRISING THE SAME CYP3A4, PPOX, CYP2C19 TSPO 924/4885KDM4E 655/4885MAPT 1143/4885
US-20230120805-A1 PHENYLCARBAZOLE-BASED COMPOUNDS AND FLUORENE-BASED COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICE AND FLAT PANEL DISPLAY DEVICE COMPRISING THE SAME CYP3A4, PPOX, CYP2C19 TSPO 924/4885KDM4E 655/4885MAPT 1143/4885
US-20240244963-A1 PHENYLCARBAZOLE-BASED COMPOUNDS AND FLUORENE-BASED COMPOUNDS AND ORGANIC LIGHT EMITTING DEVICE AND FLAT PANEL DISPLAY DEVICE COMPRISING THE SAME CYP3A4, PPOX, CYP2C19 TSPO 924/4885KDM4E 655/4885MAPT 1143/4885
US-11563178-B2 Organic electroluminescent element, compound for use in the element, and light emitting device, display device, and illumination device using the element L1CAM, RER1, H1-0 TSPO 2709/4885KDM4E 3994/4885MAPT 4091/4885
US-11700769-B2 Organic electroluminescent element, compound, and light emitting device, display device and lighting system, using said element ALDH1A2, AOC2, AOX1 TSPO 1443/4885KDM4E 1161/4885MAPT 679/4885
US-10573821-B2 Phenylcarbazole-based compounds and fluorene-based compounds and organic light emitting device and flat panel display device comprising the same CYP3A4, PPOX, CYP2C19 TSPO 924/4885KDM4E 655/4885MAPT 1143/4885
US-11844229-B2 Electroluminescent element, and light emitting device, display device and lighting device each using organic electroluminescent element LAS1L, CCNL2, CDC5L TSPO 2610/4885KDM4E 888/4885MAPT 2694/4885
US-20200203648-A1 Electroluminescent Element, And Light Emitting Device, Display Device And Lighting Device Each Using Organic Electroluminescent Element LAS1L, CCNL2, CDC5L TSPO 2610/4885KDM4E 888/4885MAPT 2694/4885
US-20200058883-A1 ORGANIC ELECTRIC LIGHT EMITTING ELEMENT, MATERIAL FOR SAID ELEMENT, AND LIGHT EMITTING DEVICE, DISPLAY DEVICE, AND ILLUMINATION DEVICE EMPLOYING SAID ELEMENT NR0B1, NR2E1, NR1D1 TSPO 3153/4885KDM4E 3180/4885MAPT 3745/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.