SCHEMBL893047

SCHEMBL893047

CCCC([C]=O)C(=O)OC

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
ZDHHC7 Q9NXF8 1/20 0.41
HDAC7 Q8WUI4 2/20 0.35
HDAC8 Q9BY41 2/20 0.35
HDAC6 Q9UBN7 2/20 0.35
HDAC9 Q9UKV0 2/20 0.35
HDAC5 Q9UQL6 2/20 0.35
SMN1; SMN2 Q16637 2/20 0.34
HDAC1 Q13547 2/20 0.34
HDAC2 Q92769 2/20 0.34
CHRM1 P11229 1/20 0.34
AKR1A1 P14550 1/20 0.34
CHRM3 P20309 1/20 0.34
HTR2A P28223 1/20 0.34
HTR2C P28335 1/20 0.34
ADRA1A P35348 1/20 0.34
HRH1 P35367 1/20 0.34
DRD3 P35462 1/20 0.34
SLC6A3 Q01959 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7291632 0.88 CA2 (0.55) CA1CA2ZDHHC7TDP1CYP3A4
SCHEMBL893477 0.84 ZDHHC7 (0.58) CA1CA2ZDHHC7ABCB1USP2
SCHEMBL9771153 0.83 ALDH1A1 (0.39) HDAC1HDAC2CHRM1AKR1A1CHRM3
SCHEMBL893423 0.82
SCHEMBL10526563 0.81 CA1 (0.42) CA1CA2ZDHHC7HDAC7HDAC8
SCHEMBL27953318 0.78 ALDH1A1 (0.47) CA1CA2SMN1; SMN2TDP1TSHR
SCHEMBL27953314 0.78 CTSK (0.39) CA1CA2HDAC1HDAC2CHRM1
SCHEMBL9201386 0.76 SMN1; SMN2 (0.36) CA1CA2ZDHHC7SMN1; SMN2MGAM
SCHEMBL10825100 0.75
SCHEMBL3127134 0.75

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103664595-B Ether ester compound and application thereof CHINA PETROLEUM & CHEMICAL 2015-07-22 CN claimed
US-20030120077-A1 Hydroxy substituted N-alkoxy hindered amines and compositions stabilized therewith GALBO JAMES PETER (US) 2003-06-26 US claimed
US-6403681-B2 STABILIZER FOR PLASTICS CIBA SPECIALTY CHEMICALS CORPORATION 2002-06-11 US claimed
US-20020058735-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith GALBO JAMES PETER (US) 2002-05-16 US claimed
US-20020040145-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith GALBO JAMES P (US) 2002-04-04 US claimed
US-20010034449-A1 Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith GALBO JAMES P (US) 2001-10-25 US claimed
US-20010031872-A1 Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith GALBO JAMES P (US) 2001-10-18 US claimed
US-20010018520-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith GALBO JAMES P (US) 2001-08-30 US claimed
US-6271377-B1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith CIBA SPECIALTY CHEMICALS CORPORATION 2001-08-07 US claimed
US-6391949-B1 None US disclosed
CN-108623456-A The preparation method of butylphenyl phthaleine and its pharmaceutical intermediate 齐鲁制药有限公司 2018-10-09 CN disclosed
CN-103665199-B A kind of ingredient of solid catalyst for olefinic polymerization, catalyzer and application SINOPEC CORP. (CN) 2015-11-25 CN disclosed
CN-103664595-B Ether ester compound and application thereof CHINA PETROLEUM & CHEMICAL 2015-07-22 CN disclosed
CN-103665199-A Solid catalyst component for olefine polymerization, catalyst and application CHINA PETROLEUM & CHEMICAL 2014-03-26 CN disclosed
US-20010034449-A1 Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith GALBO JAMES P (US) 2001-10-25 US disclosed
US-20010031872-A1 Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith GALBO JAMES P (US) 2001-10-18 US disclosed
US-20010020099-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith GALBO JAMES P (US) 2001-09-06 US disclosed
US-20010018520-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith GALBO JAMES P (US) 2001-08-30 US disclosed
US-20010016658-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith GALBO JAMES P (US) 2001-08-23 US disclosed
US-6271377-B1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith CIBA SPECIALTY CHEMICALS CORPORATION 2001-08-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020040145-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith POLH, OGG1, OGFOD1 CA1 3271/4885CA2 4697/4885ZDHHC7 1018/4885
US-20020058735-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith OGG1, HAO2, POLH CA1 2999/4885CA2 4629/4885ZDHHC7 1239/4885
US-20010016658-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith POLH, OGG1, OGFOD1 CA1 3271/4885CA2 4697/4885ZDHHC7 1018/4885
US-20010034449-A1 Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith POLH, OGG1, OGFOD1 CA1 3271/4885CA2 4697/4885ZDHHC7 1018/4885
US-20010020099-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith POLH, OGG1, OGFOD1 CA1 3271/4885CA2 4697/4885ZDHHC7 1018/4885
US-20030120077-A1 Hydroxy substituted N-alkoxy hindered amines and compositions stabilized therewith OGG1, POLH, OGFOD1 CA1 3317/4885CA2 4635/4885ZDHHC7 1158/4885
US-20010018520-A1 Hydroxy-substituted N-alkoxy hindered amines and compositions stabilized therewith POLH, OGG1, OGFOD1 CA1 3271/4885CA2 4697/4885ZDHHC7 1018/4885
US-20010031872-A1 Hydroxy-substituted N-Alkoxy hindered amines and compositions stabilized therewith POLH, OGG1, OGFOD1 CA1 3271/4885CA2 4697/4885ZDHHC7 1018/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.