Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | THRA | P10827 | 4/20 | 0.45 |
| ▸ | THRB | P10828 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30522290 | 0.92 | THRA (0.47) | SMN1; SMN2MEN1KMT2AALDH1A1POLB | |
| SCHEMBL21821361 | 0.92 | THRA (0.47) | SMN1; SMN2MEN1KMT2AALDH1A1POLB | |
| SCHEMBL195058 | 0.85 | PTGS2 (0.46) | SMN1; SMN2MEN1KMT2AALDH1A1CYP1A2 | |
| SCHEMBL15151735 | 0.81 | MAPT (0.43) | SMN1; SMN2MEN1KMT2AALDH1A1POLB | |
| SCHEMBL9786146 | 0.81 | THRB (0.59) | SMN1; SMN2MEN1KMT2AALDH1A1POLB | |
| SCHEMBL5254326 | 0.79 | CYP1A2 (0.41) | SMN1; SMN2MEN1KMT2AALDH1A1POLB | |
| SCHEMBL5269345 | 0.79 | PTGS2 (0.47) | SMN1; SMN2MEN1KMT2AALDH1A1POLB | |
| SCHEMBL7295793 | 0.79 | LTA4H (0.46) | SMN1; SMN2MEN1KMT2AALDH1A1POLB | |
| SCHEMBL7295790 | 0.79 | ALDH1A1 (0.42) | SMN1; SMN2MEN1KMT2AALDH1A1POLB | |
| SCHEMBL13062423 | 0.78 | CCNB2 (0.46) | SMN1; SMN2MEN1KMT2AALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8188144-B2 | In vitro preservation of living animal cells and compounds suitable for use in the preservation of living animal cells | ANTOXIS LIMITED (GB) | 2012-05-29 | — | — | US | disclosed |
| US-20100267132-A1 | IN VITRO PRESERVATION OF LIVING ANIMAL CELLS AND COMPOUNDS SUITABLE FOR USE IN THE PRESERVATION OF LIVING ANIMAL CELLS | ANTOXIS LIMITED (GB) | 2010-10-21 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100267132-A1 | IN VITRO PRESERVATION OF LIVING ANIMAL CELLS AND COMPOUNDS SUITABLE FOR USE IN THE PRESERVATION OF LIVING ANIMAL CELLS | PIGS, AQP1, F12 | SMN1; SMN2 719/4885MEN1 731/4885KMT2A 3131/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.