Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.40 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.37 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.36 |
| ▸ | ERBB2 | P04626 | 2/20 | 0.36 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9897504 | 0.85 | GPR119 (0.46) | MTNR1AMTNR1BGPR119 | |
| SCHEMBL8066339 | 0.84 | CA2 (0.43) | CA1CA2CYP4F2CYP4A11ALDH1A1 | |
| SCHEMBL27572251 | 0.84 | CA2 (0.55) | CA1CA2CA12CA9CA14 | |
| SCHEMBL184666 | 0.81 | CYP4F2 (0.56) | MAPTCA1CA2CA12CA9 | |
| SCHEMBL23930060 | 0.81 | CA2 (0.41) | MTNR1AMTNR1BRIPK1RIPK3CA1 | |
| SCHEMBL2427540 | 0.80 | MAPT (0.56) | MTNR1AMTNR1BMAPTCYP1A2CYP2C9 | |
| SCHEMBL2083561 | 0.79 | POLB (0.46) | CA1CA2CA12CA9EGFR | |
| SCHEMBL119585 | 0.79 | LMNA (0.54) | MAPTCYP1A2CYP2C9CYP4F2CYP4A11 | |
| SCHEMBL19085086 | 0.78 | MTNR1A (0.47) | MTNR1AMTNR1BRIPK1RIPK3MAPT | |
| SCHEMBL21554546 | 0.78 | CA2 (0.50) | MTNR1AMTNR1BCA2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1996023543-A1 | PHOTOLYTIC DRUG DELIVERY SYSTEMS | ANGIOMEDICS II INCORPORATED (US) | 1996-08-08 | — | — | WO | disclosed |