Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR119 | Q8TDV5 | 13/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.43 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.43 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23930060 | 0.86 | CA2 (0.41) | GPR119MTNR1AMTNR1B | |
| SCHEMBL8934772 | 0.85 | MTNR1A (0.42) | GPR119MTNR1AMTNR1B | |
| SCHEMBL27572251 | 0.85 | CA2 (0.55) | — | |
| SCHEMBL1096091 | 0.81 | CYP4F2 (0.58) | EPHX2NR1H4ENPP2 | |
| SCHEMBL19085086 | 0.79 | MTNR1A (0.47) | MTNR1AMTNR1B | |
| SCHEMBL21554546 | 0.79 | CA2 (0.50) | EPHX2NR1H4MTNR1AMTNR1B | |
| SCHEMBL1283948 | 0.79 | CA2 (0.50) | MTNR1AMTNR1B | |
| SCHEMBL7517689 | 0.79 | HPGD (0.50) | MTNR1AMTNR1B | |
| SCHEMBL2396163 | 0.78 | ENPP2 (0.50) | EPHX2NR1H4ENPP2 | |
| SCHEMBL2665963 | 0.78 | LMNA (0.56) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120149718-A1 | Amido Compounds | BROTHERTON-PLEISS CHRISTINE E (US) | 2012-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120149718-A1 | Amido Compounds | P2RX7, P2RX3, P2RX2 | GPR119 56/4885EPHX2 1765/4885NR1H4 285/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.