Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.53 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.53 |
| ▸ | FNTA | P49354 | 7/20 | 0.51 |
| ▸ | FNTB | P49356 | 7/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA1 | P00915 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | USP2 | O75604 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8936963 | 1.00 | L3MBTL1 (0.53) | L3MBTL1TAS1R3TAS1R1FNTAFNTB | |
| SCHEMBL8616092 | 0.77 | ROCK2 (0.49) | KMT2A | |
| SCHEMBL8936965 | 0.77 | FNTA (0.56) | L3MBTL1TAS1R3TAS1R1FNTAFNTB | |
| SCHEMBL7232898 | 0.77 | TAS1R3 (0.63) | L3MBTL1TAS1R3TAS1R1FNTAFNTB | |
| SCHEMBL8896137 | 0.77 | TAS1R3 (0.63) | L3MBTL1TAS1R3TAS1R1FNTAFNTB | |
| SCHEMBL2323686 | 0.76 | L3MBTL1 (0.74) | L3MBTL1TAS1R3TAS1R1FNTAFNTB | |
| SCHEMBL18095164 | 0.76 | L3MBTL1 (0.74) | L3MBTL1TAS1R3TAS1R1FNTAFNTB | |
| SCHEMBL8369449 | 0.75 | FNTA (0.68) | L3MBTL1TAS1R3TAS1R1FNTAFNTB | |
| SCHEMBL8369448 | 0.75 | FNTA (0.68) | L3MBTL1TAS1R3TAS1R1FNTAFNTB | |
| SCHEMBL8517002 | 0.75 | FNTA (0.66) | L3MBTL1TAS1R3TAS1R1FNTAFNTB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5578629-A | ANTICARCINOGENIC AGENTS | MERCK & CO., INC. (US) | 1996-11-26 | — | — | US | disclosed |
| WO-1996030015-A1 | INHIBITORS OF FARNESYL-PROTEIN TRANSFERASE | MERCK & CO., INC. (US) | 1996-10-03 | — | — | WO | disclosed |
| US-5534537-A | Prodrugs of inhibitors of farnesyl-protein transferase | MERCK & CO., INC. (US) | 1996-07-09 | — | — | US | disclosed |