Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.42 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29286665 | 0.87 | ACHE (0.50) | ACHEDRD2DRD4MAPTLMNA | |
| SCHEMBL8939051 | 0.85 | LTA4H (0.39) | LMNAL3MBTL1TDP1POLB | |
| SCHEMBL8939016 | 0.82 | DRD2 (0.36) | ACHEDRD2DRD4MAPTLMNA | |
| SCHEMBL11704410 | 0.80 | ACHE (0.50) | ACHEDRD2DRD4MAPTLMNA | |
| SCHEMBL1727164 | 0.79 | ACHE (0.44) | ACHEMAPTLMNAHTTMAPK1 | |
| SCHEMBL28448878 | 0.78 | ACHE (0.48) | ACHEDRD2DRD4MAPTLMNA | |
| SCHEMBL1726625 | 0.78 | ACHE (0.48) | ACHEDRD2DRD4MAPTLMNA | |
| SCHEMBL8939005 | 0.78 | MAPT (0.35) | MAPTLMNAHTTL3MBTL1KMT2A | |
| SCHEMBL8939008 | 0.77 | L3MBTL1 (0.38) | MAPTLMNAHTTMAPK1ALDH1A1 | |
| SCHEMBL8939007 | 0.77 | MAPT (0.38) | MAPTLMNAHTTL3MBTL1TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5498741-A | Alkyl aryl arylphosphonites, process for the preparation thereof and use thereof | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-03-12 | — | — | US | disclosed |