Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.32 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 2/20 | 0.32 |
| ▸ | HTR7 | P34969 | 2/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HTR6 | P50406 | 1/20 | 0.32 |
| ▸ | C5AR1 | P21730 | 1/20 | 0.31 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8939035 | 0.86 | SCN4A (0.37) | MAPTL3MBTL1LMNANPSR1MEN1 | |
| SCHEMBL3418221 | 0.86 | CYP1A2 (0.38) | MAPTL3MBTL1LMNANPSR1MEN1 | |
| SCHEMBL8939008 | 0.83 | L3MBTL1 (0.38) | MAPTL3MBTL1LMNAKMT2AATM | |
| SCHEMBL8939007 | 0.80 | MAPT (0.38) | MAPTL3MBTL1LMNAMEN1KMT2A | |
| SCHEMBL8939016 | 0.78 | DRD2 (0.36) | MAPTL3MBTL1LMNAMEN1KMT2A | |
| SCHEMBL911476 | 0.78 | CYP3A4 (0.39) | L3MBTL1NPSR1MEN1KMT2A | |
| SCHEMBL8939014 | 0.78 | ACHE (0.42) | MAPTL3MBTL1LMNANPSR1KMT2A | |
| SCHEMBL2693261 | 0.77 | CYP1A2 (0.36) | MAPTL3MBTL1LMNANPSR1MEN1 | |
| SCHEMBL8939051 | 0.77 | LTA4H (0.39) | L3MBTL1LMNAPOLB | |
| SCHEMBL27613359 | 0.76 | ATM (0.38) | MAPTLMNANPSR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5498741-A | Alkyl aryl arylphosphonites, process for the preparation thereof and use thereof | HOECHST AKTIENGESELLSCHAFT (DE) | 1996-03-12 | — | — | US | disclosed |