Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | KCNN4 | O15554 | 5/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Imidazole SCHEMBL6959692 | 0.83 | ALDH1A1 (0.36) | ALDH1A1TSHRHTTNPSR1KMT2A | |
| SCHEMBL22312949 | 0.72 | GRIN1 (0.67) | ALDH1A1TSHRHTTKDM4E | |
| SCHEMBL10315081 | 0.71 | ALDH1A1 (0.42) | ALDH1A1TSHRHTT | |
| SCHEMBL8939158 | 0.71 | KCNN4 (0.48) | ALDH1A1TSHRHTTNPSR1KCNN4 | |
| Biphenyl SCHEMBL28773145 | 0.71 | FFAR1 (0.52) | ALDH1A1TSHRHTTKMT2ASMN1; SMN2 | |
| SCHEMBL317112 | 0.71 | MAPT (0.57) | ALDH1A1HTTNPSR1KMT2AMEN1 | |
| SCHEMBL19419845 | 0.71 | CYP1A2 (0.47) | ALDH1A1TSHRHTTNPSR1KMT2A | |
| SCHEMBL1035978 | 0.70 | ALDH1A1 (0.53) | ALDH1A1TSHRHTTNPSR1KMT2A | |
| SCHEMBL11595736 | 0.70 | L3MBTL1 (0.42) | NPSR1KCNN4CYP2C19HIF1A | |
| SCHEMBL8939163 | 0.70 | KCNN4 (0.44) | ALDH1A1KCNN4SMN1; SMN2CYP2C19HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5532228-A | ANTITUMOR, PSORIASIS | SCHERING AKTIENGESELLSCHAFT (DE) | 1996-07-02 | — | — | US | disclosed |