Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | USP2 | O75604 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 3/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.40 |
| ▸ | HTR7 | P34969 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 5/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.39 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.39 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.39 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8939613 | 0.89 | KMT2A (0.56) | ALDH1A1LMNAUSP2HTTL3MBTL1 | |
| SCHEMBL8939603 | 0.85 | TSHR (0.48) | ALDH1A1LMNAHTTKMT2AMAPT | |
| SCHEMBL8939653 | 0.84 | HSD11B1 (0.47) | HSD11B1ALDH1A1LMNAHTTKMT2A | |
| SCHEMBL8939638 | 0.80 | MMP2 (0.49) | HSD11B1ALDH1A1LMNAUSP2HTT | |
| SCHEMBL8939673 | 0.76 | LMNA (0.50) | ALDH1A1LMNAKMT2AMAPTSMN1; SMN2 | |
| SCHEMBL8939707 | 0.75 | ALDH1A1 (0.60) | ALDH1A1LMNAUSP2KMT2AMAPT | |
| SCHEMBL9223966 | 0.73 | LMNA (0.44) | ALDH1A1LMNAL3MBTL1KMT2AMAPT | |
| SCHEMBL2961026 | 0.72 | CHRM4 (0.62) | HSD11B1ALDH1A1LMNAKMT2AMAPT | |
| SCHEMBL8939597 | 0.70 | LMNA (0.46) | ALDH1A1LMNAHTTKMT2AMAPT | |
| SCHEMBL9019620 | 0.69 | KDM4E (0.40) | HSD11B1ALDH1A1LMNAKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0626369-B1 | BENZENESULFONAMIDE DERIVATIVE | KYOWA HAKKO KOGYO KK (JP) | 1996-09-18 | — | — | EP | disclosed |
| US-5523464-A | BONE DISORDERS | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1996-06-04 | — | — | US | disclosed |
| EP-0626369-A1 | BENZENESULFONAMIDE DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1994-11-30 | — | — | EP | disclosed |