Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | RAB9A | P51151 | 2/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | FABP1 | P07148 | 1/20 | 0.42 |
| ▸ | TNKS | O95271 | 1/20 | 0.42 |
| ▸ | PARP15 | Q460N3 | 1/20 | 0.42 |
| ▸ | PARP14 | Q460N5 | 1/20 | 0.42 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.42 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.42 |
| ▸ | PARP2 | Q9UGN5 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.41 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942429 | 0.88 | PARP10 (0.45) | HPGDTNKSPARP15PARP14PARP10 | |
| SCHEMBL8942712 | 0.86 | PARP14 (0.45) | TNKSPARP15PARP14PARP10TNKS2 | |
| SCHEMBL8782866 | 0.85 | MEN1 (0.51) | MAPTHPGDRECQLNPSR1NPC1 | |
| SCHEMBL8942507 | 0.84 | KDM4E (0.43) | MAPTPOLBNR4A2 | |
| SCHEMBL8942661 | 0.83 | KMO (0.53) | NPSR1TNKSPARP15PARP14PARP10 | |
| SCHEMBL8942753 | 0.82 | PARP1 (0.52) | MAPTHPGDNPC1RAB9AMEN1 | |
| SCHEMBL8942408 | 0.81 | TNKS (0.39) | MAPTNPSR1NPC1RAB9ATNKS | |
| SCHEMBL8942402 | 0.80 | EPOR (0.46) | MAPTNPC1TNKSPARP15PARP14 | |
| SCHEMBL8942585 | 0.80 | MEN1 (0.42) | NPC1RAB9APARP10MEN1KMT2A | |
| SCHEMBL8942484 | 0.79 | PARP10 (0.50) | HPGDNPC1POLBRAB9APARP10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514702-A | Arylamidoalkyl-N-hydroxyurea compounds having lipoxygenase inhibitory activity | ABBOTT LABORATORIES (US) | 1996-05-07 | — | — | US | disclosed |