Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.41 |
| ▸ | F10 | P00742 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.39 |
| ▸ | ACR | P10323 | 1/20 | 0.39 |
| ▸ | GHSR | Q92847 | 1/20 | 0.39 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.39 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8782309 | 0.85 | POLB (0.52) | KDM4EMAPK14ALDH1A1POLBMRGPRX4 | |
| SCHEMBL8942679 | 0.84 | MAPT (0.47) | POLBNR4A2MAPT | |
| SCHEMBL8942712 | 0.82 | PARP14 (0.45) | MRGPRX4NR4A2PPARG | |
| SCHEMBL8942408 | 0.82 | TNKS (0.39) | ALDH1A1MRGPRX4MAPT | |
| SCHEMBL8942429 | 0.82 | PARP10 (0.45) | ALDH1A1 | |
| SCHEMBL8942661 | 0.81 | KMO (0.53) | ALDH1A1MRGPRX4CHEK2 | |
| SCHEMBL8942753 | 0.80 | PARP1 (0.52) | ALDH1A1GAAMAPTTDP1PRSS1 | |
| SCHEMBL8942402 | 0.79 | EPOR (0.46) | MAPT | |
| SCHEMBL8942585 | 0.78 | MEN1 (0.42) | KDM4EALDH1A1F10GAATDP1 | |
| SCHEMBL8942628 | 0.77 | SCN7A (0.43) | F10PPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514702-A | Arylamidoalkyl-N-hydroxyurea compounds having lipoxygenase inhibitory activity | ABBOTT LABORATORIES (US) | 1996-05-07 | — | — | US | disclosed |