Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RORC | P51449 | 2/20 | 0.48 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.42 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8979006 | 0.84 | ALDH1A1 (0.53) | RORCPTGS2CYP19A1MEN1PTGES | |
| SCHEMBL8942563 | 0.83 | RORC (0.47) | RORCPTGS2CYP19A1MEN1PTGES | |
| SCHEMBL8942579 | 0.80 | MEN1 (0.47) | RORCPTGS2CYP19A1MEN1PTGES | |
| SCHEMBL8979019 | 0.79 | PTGS2 (0.49) | RORCPTGS2CYP19A1MEN1PTGES | |
| SCHEMBL9235400 | 0.76 | PTGS2 (0.46) | RORCPTGS2CYP19A1MEN1PTGES | |
| SCHEMBL8979023 | 0.75 | PTGS2 (0.57) | PTGS2CYP19A1MEN1PTGESALDH1A1 | |
| SCHEMBL9233770 | 0.70 | PTGS2 (0.42) | RORCPTGS2CYP19A1MEN1PTGES | |
| SCHEMBL9233767 | 0.70 | PTGS2 (0.47) | PTGS2CYP19A1MEN1PTGESALDH1A1 | |
| SCHEMBL8523784 | 0.70 | PTGS1 (0.61) | PTGS2CYP19A1MEN1PTGESALDH1A1 | |
| SCHEMBL8942521 | 0.69 | CYP19A1 (0.82) | PTGS2CYP19A1MEN1PTGESALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521311-A | USEFUL AS ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, ANALGESICS AND ANTI-ALLERGENIC AGENTS | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |