Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.49 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | PTGES | O14684 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | PDE4A | P27815 | 2/20 | 0.41 |
| ▸ | BRD4 | O60885 | 3/20 | 0.41 |
| ▸ | EP300 | Q09472 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 2/20 | 0.40 |
| ▸ | RORC | P51449 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8979006 | 0.83 | ALDH1A1 (0.53) | PTGS2CYP19A1MEN1PTGESALDH1A1 | |
| Propylamine SCHEMBL8942567 | 0.79 | RORC (0.48) | PTGS2CYP19A1MEN1PTGESALDH1A1 | |
| SCHEMBL8978983 | 0.78 | CYP19A1 (0.60) | PTGS2CYP19A1MEN1PTGESALDH1A1 | |
| SCHEMBL8942563 | 0.78 | RORC (0.47) | PTGS2CYP19A1MEN1PTGESALDH1A1 | |
| SCHEMBL8979023 | 0.76 | PTGS2 (0.57) | PTGS2CYP19A1MEN1PTGESALDH1A1 | |
| SCHEMBL8942579 | 0.75 | MEN1 (0.47) | PTGS2CYP19A1MEN1PTGESALDH1A1 | |
| SCHEMBL8523784 | 0.73 | PTGS1 (0.61) | PTGS2CYP19A1MEN1PTGESALDH1A1 | |
| SCHEMBL9235400 | 0.72 | PTGS2 (0.46) | PTGS2CYP19A1MEN1PTGESALDH1A1 | |
| SCHEMBL8942521 | 0.72 | CYP19A1 (0.82) | PTGS2CYP19A1MEN1PTGESALDH1A1 | |
| SCHEMBL11935716 | 0.71 | CARM1 (0.38) | MAPTPDE4ARORCPDE4BPDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641774-B1 | 5-AMINOSULFONANILIDE COMPOUND | TAISHO PHARMACEUTICAL CO LTD (JP) | 1996-05-08 | — | — | EP | disclosed |
| EP-0641774-A1 | 5-AMINOSULFONANILIDE COMPOUND | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1995-03-08 | — | — | EP | disclosed |
| US-5374764-A | Antiinflammatory agens, antipyretics, analgesics and antiallergens | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1994-12-20 | — | — | US | disclosed |