Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.46 |
| ▸ | PTGES | O14684 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | RORC | P51449 | 1/20 | 0.46 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942563 | 0.88 | RORC (0.47) | MEN1KMT2APTGS2ALDH1A1KDM4E | |
| SCHEMBL8979006 | 0.84 | ALDH1A1 (0.53) | MEN1KMT2APTGS2ALDH1A1MAPT | |
| Propylamine SCHEMBL8942567 | 0.80 | RORC (0.48) | MEN1KMT2APTGS2ALDH1A1MAPT | |
| SCHEMBL8979019 | 0.75 | PTGS2 (0.49) | MEN1KMT2APTGS2ALDH1A1MAPT | |
| SCHEMBL8979023 | 0.74 | PTGS2 (0.57) | MEN1KMT2APTGS2ALDH1A1MAPT | |
| SCHEMBL9233767 | 0.73 | PTGS2 (0.47) | MEN1KMT2APTGS2ALDH1A1MAPT | |
| SCHEMBL8523784 | 0.70 | PTGS1 (0.61) | MEN1KMT2APTGS2ALDH1A1MAPT | |
| SCHEMBL9235400 | 0.70 | PTGS2 (0.46) | MEN1KMT2APTGS2ALDH1A1MAPT | |
| SCHEMBL8942521 | 0.70 | CYP19A1 (0.82) | MEN1KMT2APTGS2ALDH1A1KDM4E | |
| SCHEMBL21663533 | 0.70 | POLB (0.68) | POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5521311-A | USEFUL AS ANTIINFLAMMATORY AGENTS, ANTIPYRETICS, ANALGESICS AND ANTI-ALLERGENIC AGENTS | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1996-05-28 | — | — | US | disclosed |
| EP-0685461-A1 | 5-AMINOACETYLAMINOSULFONANILIDE COMPOUND | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1995-12-06 | — | — | EP | disclosed |