Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.53 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.46 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | PTGES | O14684 | 1/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.45 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8942563 | 0.87 | RORC (0.47) | ALDH1A1RORCSMN1; SMN2LMNAPTGS2 | |
| SCHEMBL8942579 | 0.84 | MEN1 (0.47) | ALDH1A1RORCSMN1; SMN2LMNAPTGS2 | |
| Propylamine SCHEMBL8942567 | 0.84 | RORC (0.48) | ALDH1A1RORCSMN1; SMN2PTGS2CYP19A1 | |
| SCHEMBL8979019 | 0.83 | PTGS2 (0.49) | ALDH1A1RORCSMN1; SMN2PTGS2CYP19A1 | |
| SCHEMBL8978970 | 0.80 | CYP19A1 (0.53) | ALDH1A1HTTSMN1; SMN2PTGS2CYP19A1 | |
| SCHEMBL9235400 | 0.73 | PTGS2 (0.46) | ALDH1A1RORCSMN1; SMN2PTGS2CYP19A1 | |
| SCHEMBL8979070 | 0.73 | CYP19A1 (0.55) | ALDH1A1SMN1; SMN2LMNAPTGS2CYP19A1 | |
| SCHEMBL8979023 | 0.73 | PTGS2 (0.57) | ALDH1A1SMN1; SMN2PTGS2CYP19A1CYP1A2 | |
| SCHEMBL10115496 | 0.73 | ALDH1A1 (0.43) | ALDH1A1HTTRORCSMN1; SMN2LMNA | |
| SCHEMBL10115258 | 0.73 | ALDH1A1 (0.46) | ALDH1A1HTTRORCSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0641774-B1 | 5-AMINOSULFONANILIDE COMPOUND | TAISHO PHARMACEUTICAL CO LTD (JP) | 1996-05-08 | — | — | EP | disclosed |
| EP-0641774-A1 | 5-AMINOSULFONANILIDE COMPOUND | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1995-03-08 | — | — | EP | disclosed |
| US-5374764-A | Antiinflammatory agens, antipyretics, analgesics and antiallergens | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1994-12-20 | — | — | US | disclosed |