SCHEMBL8945172

SCHEMBL8945172

CCc1cc(CC2(C)CCC(c3ccccc3)CC2)ccc1N

nearest known ligand 0.35

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SIGMAR1 Q99720 1/20 0.35
DRD2 P14416 1/20 0.35
MAPT P10636 2/20 0.34
ALDH1A1 P00352 1/20 0.34
TRPA1 O75762 1/20 0.34
NR3C1 P04150 1/20 0.34
KDM1A O60341 2/20 0.33
MAOA P21397 2/20 0.33
MAOB P27338 2/20 0.33
DHFR P00374 1/20 0.33
NPC1 O15118 1/20 0.33
STAT1 P42224 1/20 0.33
RAB9A P51151 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
BACE1 P56817 1/20 0.33
ATP1A1 P05023 1/20 0.33
ATP1B1 P05026 1/20 0.33
ATP1A3 P13637 1/20 0.33
ATP1B2 P14415 1/20 0.33
ATP1A2 P50993 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8945007 0.90 DHFR (0.39) SIGMAR1DRD2TRPA1KDM1AMAOA
SCHEMBL8945160 0.73 HTR6 (0.36) MAPTMAOAMAOBMEN1KMT2A
SCHEMBL8945400 0.70 NOS3 (0.41) MAPTALDH1A1RAB9ABACE1MEN1
SCHEMBL10286692 0.70 ALDH1A1 (0.38) MAPTALDH1A1DHFRRAB9ABACE1
SCHEMBL8945278 0.70 HTR2C (0.46) DRD2ALDH1A1ATP1A1ATP1B1ATP1A3
SCHEMBL8945105 0.70 DRD2 (0.44) DRD2MAOAMAOBDHFRATP1A1
SCHEMBL8945167 0.69 ESR2 (0.41) MAPTALDH1A1DHFRRAB9AMEN1
SCHEMBL8945344 0.69 KDM1A (0.39) KDM1AMAOB
SCHEMBL8945024 0.67 CYP2C9 (0.51) MAPTALDH1A1MEN1KMT2A
SCHEMBL9910784 0.67 ALDH1A1 (0.40) MAPTALDH1A1DHFRBACE1ATP4A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5501884-A Diamino compounds and their production method and liquid crystal alignment layers using the compounds CHISSO CORPORATION (JP) 1996-03-26 US disclosed