Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.38 |
| ▸ | MMP8 | P22894 | 4/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.36 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945836 | 0.71 | OPRK1 (0.41) | LMNACYP3A4ALDH1A1RIPK1MMP8 | |
| SCHEMBL2202821 | 0.69 | MAPT (0.43) | LMNACYP2D6CYP3A4CYP1A2RECQL | |
| SCHEMBL11853018 | 0.69 | KCNA5 (0.49) | LMNACYP2D6CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL3680427 | 0.68 | FDPS (0.47) | ALDH1A1GAAMAPTRAB9AHIF1A | |
| Hydrochloric Acid SCHEMBL11851894 | 0.67 | KCNA5 (0.47) | LMNACYP2D6CYP3A4CYP1A2MAPK1 | |
| SCHEMBL6017676 | 0.67 | MMP8 (0.67) | MAPK1ALDH1A1RIPK1MMP8GAA | |
| SCHEMBL24867392 | 0.67 | ROCK2 (0.38) | LMNAMAPK1ALDH1A1MMP8RAB9A | |
| SCHEMBL28898673 | 0.66 | MMP8 (0.48) | LMNACYP2D6CYP3A4CYP1A2RECQL | |
| SCHEMBL1147656 | 0.66 | SLC6A2 (0.52) | LMNACYP2D6CYP3A4CYP1A2RECQL | |
| SCHEMBL517462 | 0.66 | SMN1; SMN2 (0.57) | LMNACYP2D6CYP3A4CYP1A2RECQL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510346-A | ANTIDEPRESSANTS, ANTIANXIETY AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1996-04-23 | — | — | US | disclosed |