Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRK1 | P41145 | 3/20 | 0.41 |
| ▸ | RIPK1 | Q13546 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.38 |
| ▸ | MMP8 | P22894 | 2/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8945943 | 0.87 | L3MBTL1 (0.44) | OPRK1LMNACYP3A4ADRB3 | |
| SCHEMBL8945854 | 0.82 | RIPK1 (0.40) | OPRK1RIPK1ALDH1A1CYP3A4MMP8 | |
| SCHEMBL8945899 | 0.81 | OPRK1 (0.41) | OPRK1RIPK1ALDH1A1MMP8ADRB3 | |
| SCHEMBL8945920 | 0.80 | MMP1 (0.42) | OPRK1RIPK1LMNACYP3A4MMP8 | |
| SCHEMBL8945941 | 0.79 | RIPK1 (0.39) | OPRK1RIPK1LMNAALDH1A1MMP8 | |
| SCHEMBL8945878 | 0.75 | RIPK1 (0.39) | OPRK1RIPK1MMP8 | |
| SCHEMBL31461498 | 0.72 | OPRK1 (0.43) | OPRK1RIPK1ALDH1A1 | |
| SCHEMBL1883138 | 0.71 | RIPK1 (0.47) | OPRK1RIPK1ALDH1A1CYP3A4MMP8 | |
| SCHEMBL8946029 | 0.71 | LMNA (0.41) | RIPK1LMNAALDH1A1CYP3A4GAA | |
| SCHEMBL9321453 | 0.71 | SLC6A2 (0.59) | ALDH1A1CYP3A4GAAADRB3SLC6A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5510346-A | ANTIDEPRESSANTS, ANTIANXIETY AGENTS | HOECHST MARION ROUSSEL, INC. (US) | 1996-04-23 | — | — | US | disclosed |