Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 4/20 | 0.73 |
| ▸ | HTR1D | P28221 | 2/20 | 0.73 |
| ▸ | HTR1A | P08908 | 1/20 | 0.73 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.73 |
| ▸ | HTR7 | P34969 | 1/20 | 0.73 |
| ▸ | HTR5A | P47898 | 1/20 | 0.73 |
| ▸ | MTNR1A | P48039 | 4/20 | 0.66 |
| ▸ | MTNR1B | P49286 | 4/20 | 0.66 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.66 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.66 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.66 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.66 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.66 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.66 |
| ▸ | HPGD | P15428 | 1/20 | 0.66 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.66 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.66 |
| ▸ | TUBB4A | P04350 | 1/20 | 0.62 |
| ▸ | TUBB | P07437 | 1/20 | 0.62 |
| ▸ | TUBA3C | P0DPH7 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7613059 | 0.85 | KDM4E (0.64) | HTR6HTR1DHTR1ASLC6A4HTR7 | |
| SCHEMBL29423321 | 0.85 | HTR6 (1.00) | HTR6HTR1DHTR1ASLC6A4HTR7 | |
| SCHEMBL5763578 | 0.85 | HTR6 (1.00) | HTR6HTR1DHTR1ASLC6A4HTR7 | |
| SCHEMBL8946961 | 0.81 | HTR6 (0.72) | HTR6HTR1DHTR1ASLC6A4HTR7 | |
| Oxalic Acid SCHEMBL5781188 | 0.80 | HTR6 (0.89) | HTR6HTR1DHTR1ASLC6A4HTR7 | |
| SCHEMBL3508630 | 0.80 | MTNR1A (1.00) | MTNR1AMTNR1BKDM4EALDH1A1CYP1A2 | |
| SCHEMBL29759426 | 0.80 | MTNR1A (1.00) | MTNR1AMTNR1BKDM4EALDH1A1CYP1A2 | |
| SCHEMBL4875370 | 0.80 | HTR6 (0.70) | HTR6KDM4EALDH1A1MAPTKMT2A | |
| SCHEMBL8802574 | 0.80 | MTNR1A (0.67) | HTR6HTR1DHTR1ASLC6A4HTR7 | |
| SCHEMBL4244966 | 0.79 | HTR1D (1.00) | HTR6HTR1DHTR1AHTR7HTR5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5552428-A | ANTIARRHYTHMIA AGENTS FOR CARDIOVASCULAR DISORDERS USING MELATONIN DERIVATIVES | INSTITUTO FARMACOLOGICO LOMBARDO-IFLO, S.A.S. (IT) | 1996-09-03 | — | — | US | disclosed |