Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | HTR1A | P08908 | 4/20 | 0.50 |
| ▸ | HTR7 | P34969 | 4/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CNR2 | P34972 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | RAB9A | P51151 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8947958 | 0.87 | SMN1; SMN2 (0.55) | LMNAGAANPC1MAPTRAB9A | |
| SCHEMBL8947975 | 0.84 | SIGMAR1 (0.56) | HTT | |
| SCHEMBL8947939 | 0.83 | DRD2 (0.53) | CNR2 | |
| SCHEMBL8948121 | 0.82 | HTR2A (0.57) | TSHRLMNAHTR1AHTR7KDM4E | |
| SCHEMBL8948100 | 0.80 | SIGMAR1 (0.48) | — | |
| SCHEMBL8948051 | 0.77 | HTR2A (0.55) | LMNAHTTHTR7ALDH1A1SMN1; SMN2 | |
| SCHEMBL8948150 | 0.77 | HTR2A (0.55) | LMNAHTTHTR7CNR2ALDH1A1 | |
| SCHEMBL11707845 | 0.77 | KDM4E (0.58) | KDM4E | |
| SCHEMBL8948192 | 0.75 | HTR1A (0.65) | HTR1AHTR7 | |
| SCHEMBL12359944 | 0.74 | SIGMAR1 (0.74) | CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5534517-A | (Aryl(alkyl)carbonyl)-heterocyclic compounds and their use in the treatment of anxiety and depression | ADIR ET COMPAGNIE (FR) | 1996-07-09 | — | — | US | disclosed |
| US-5387586-A | Analgesics, nervous system disorders | ADIR ET COMPAGNIE (FR) | 1995-02-07 | — | — | US | disclosed |