SCHEMBL895027

SCHEMBL895027

NC(CCCCB(O)O)(CCN1CCCCC1)C(=O)O

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
ARG1 P05089 19/20 1.00
ARG2 P78540 18/20 1.00

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10207709 1.00 ARG1 (1.00) ARG1ARG2
SCHEMBL895025 1.00 ARG1 (1.00) ARG1ARG2
SCHEMBL895311 0.99 ARG1 (1.00) ARG1ARG2
SCHEMBL20539769 0.99 ARG1 (1.00) ARG1ARG2
SCHEMBL895040 0.96 ARG1 (0.94) ARG1ARG2
SCHEMBL894843 0.94 ARG1 (0.89) ARG1ARG2
Hydrochloric Acid SCHEMBL894984 0.94 ARG1 (0.92) ARG1ARG2
Hydrochloric Acid SCHEMBL895176 0.93 ARG1 (0.87) ARG1ARG2
Hydrochloric Acid SCHEMBL895733 0.93 ARG1 (0.89) ARG1ARG2
SCHEMBL10006081 0.93 ARG1 (0.89) ARG1ARG2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 131 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4659023-A1 METHOD OF PREDICTING SUCCESS OF A CANCER THERAPY Immusmol SAS (FR) 2025-12-10 EP claimed
WO-2024161038-A1 METHOD OF PREDICTING SUCCESS OF A CANCER THERAPY IMMUSMOL SAS (FR) 2024-08-08 WO claimed
EP-3696281-A1 ARGINASE AS BIOMARKER AND DRUG TARGET FOR PCOS Johann Wolfgang Goethe-Universität Frankfurt am Main (DE) 2020-08-19 EP claimed
US-12569445-B2 Particles comprising a therapeutic or diagnostic agent and suspensions and methods of use thereof HALOZYME HYPERCON, INC. (US) 2026-03-10 US disclosed
US-12558323-B2 Particle formation and morphology ELEKTROFI, INC. (US) 2026-02-24 US disclosed
US-20260049087-A1 SOLID FORMS OF ISOQUINOLINONES, AND PROCESS OF MAKING, COMPOSITION COMPRISING, AND METHODS OF USING THE SAME TWELVE THERAPEUTICS INC (US) 2026-02-19 US disclosed
US-20260007615-A1 PARTICLES COMPRISING A THERAPEUTIC OR DIAGNOSTIC AGENT AND SUSPENSIONS AND METHODS OF USE THEREOF ELEKTROFI INC (US) 2026-01-08 US disclosed
US-20260000616-A1 METHODS OF FORMING PARTICLES BY CONTINUOUS DROPLET FORMATION AND DEHYDRATION ELEKTROFI INC (US) 2026-01-01 US disclosed
US-20250383333-A1 DETERMINATION OF PARTICULATE CONTAMINANTS IN PARTICLES AND COMPOSITIONS ELEKTROFI INC (US) 2025-12-18 US disclosed
EP-4659023-A1 METHOD OF PREDICTING SUCCESS OF A CANCER THERAPY Immusmol SAS (FR) 2025-12-10 EP disclosed
US-12433849-B2 Particles comprising a therapeutic or diagnostic agent and suspensions and methods of use thereof ELEKTROFI, INC. (US) 2025-10-07 US disclosed
US-20170088553-A1 SOLID FORMS OF ISOQUINOLINONES, AND PROCESS OF MAKING, COMPOSITION COMPRISING, AND METHODS OF USING THE SAME TWELVE THERAPEUTICS, INC. 2017-03-30 US disclosed
US-20170087221-A1 NITRIC OXIDE-MODULATING BONE-TARGETING COMPLEXES ELWHA LLC 2017-03-30 US disclosed
WO-2017048702-A1 SOLID FORMS OF ISOQUINOLINONE DERIVATIVES, PROCESS OF MAKING, COMPOSITIONS COMPRISING, AND METHODS OF USING THE SAME INFINITY PHARMACEUTICALS, INC. (US) 2017-03-23 WO disclosed
WO-2016100619-A2 TREATMENT AND DIAGNOSIS OF CANCER RGENIX, INC. (US) 2016-06-23 WO disclosed
US-20150290207-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF TWELVE THERAPEUTICS, INC. 2015-10-15 US disclosed
US-9040703-B2 Inhibitors of arginase and their therapeutic applications MARS, INCORPORATED (US) 2015-05-26 US disclosed
US-20140371175-A1 INHIBITORS OF ARGINASE AND THEIR THERAPEUTIC APPLICATIONS MARS, INCORPORATED 2014-12-18 US disclosed
US-20120083469-A1 INHIBITORS OF ARGINASE AND THEIR THERAPEUTIC APPLICATIONS MARS, INCORPORATED 2012-04-05 US disclosed
WO-2011133653-A1 INHIBITORS OF ARGINASE AND THEIR THERAPEUTIC APPLICATIONS MARS, INCORPORATED (US) 2011-10-27 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (9 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260000616-A1 METHODS OF FORMING PARTICLES BY CONTINUOUS DROPLET FORMATION AND DEHYDRATION ALB, TNF, TTR ARG1 2961/4885ARG2 3576/4885
US-20170088553-A1 SOLID FORMS OF ISOQUINOLINONES, AND PROCESS OF MAKING, COMPOSITION COMPRISING, AND METHODS OF USING THE SAME PIK3CA, PIK3C2A, PIK3CD ARG1 3774/4885ARG2 3537/4885
US-12569445-B2 Particles comprising a therapeutic or diagnostic agent and suspensions and methods of use thereof ALB, S100P, S100A8 ARG1 1839/4885ARG2 2268/4885
US-12558323-B2 Particle formation and morphology CD63, EXOSC10, EPCAM ARG1 488/4885ARG2 1858/4885
US-20260049087-A1 SOLID FORMS OF ISOQUINOLINONES, AND PROCESS OF MAKING, COMPOSITION COMPRISING, AND METHODS OF USING THE SAME PRKCB, PRKCD, PRKCA ARG1 1262/4885ARG2 1078/4885
US-20260007615-A1 PARTICLES COMPRISING A THERAPEUTIC OR DIAGNOSTIC AGENT AND SUSPENSIONS AND METHODS OF USE THEREOF FLNB, FLNA, FUS ARG1 2547/4885ARG2 2695/4885
US-20150290207-A1 HETEROCYCLIC COMPOUNDS AND USES THEREOF PIK3CA, PIK3CD, PIK3CB ARG1 4077/4885ARG2 2115/4885
US-20120083469-A1 INHIBITORS OF ARGINASE AND THEIR THERAPEUTIC APPLICATIONS ARG1, ARG2, PRMT9 ARG1 1/4885ARG2 2/4885
US-20140371175-A1 INHIBITORS OF ARGINASE AND THEIR THERAPEUTIC APPLICATIONS ARG1, ARG2, PRMT9 ARG1 1/4885ARG2 2/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.