Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.50 |
| ▸ | CA1 | P00915 | 5/20 | 0.48 |
| ▸ | CA2 | P00918 | 5/20 | 0.48 |
| ▸ | CA12 | O43570 | 3/20 | 0.48 |
| ▸ | CA3 | P07451 | 3/20 | 0.48 |
| ▸ | CA4 | P22748 | 3/20 | 0.48 |
| ▸ | CA6 | P23280 | 3/20 | 0.48 |
| ▸ | CA5A | P35218 | 3/20 | 0.48 |
| ▸ | CA7 | P43166 | 3/20 | 0.48 |
| ▸ | CA9 | Q16790 | 3/20 | 0.48 |
| ▸ | CA13 | Q8N1Q1 | 3/20 | 0.48 |
| ▸ | CA14 | Q9ULX7 | 3/20 | 0.48 |
| ▸ | CA5B | Q9Y2D0 | 3/20 | 0.48 |
| ▸ | MMP2 | P08253 | 2/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2152262 | 0.77 | ALDH1A1 (0.62) | ALDH1A1CYP3A4MAPK1LMNACYP2A6 | |
| SCHEMBL24062386 | 0.73 | ALDH1A1 (0.58) | ALDH1A1CYP3A4MAPK1LMNACYP2A6 | |
| SCHEMBL21585256 | 0.73 | ALDH1A1 (0.44) | ALDH1A1CYP3A4MAPK1LMNACYP2A6 | |
| SCHEMBL14430041 | 0.71 | ALDH1A1 (0.55) | ALDH1A1CYP3A4MAPK1LMNACYP2A6 | |
| SCHEMBL895617 | 0.71 | CA1 (0.44) | ALDH1A1CA1CA2CA7CA9 | |
| SCHEMBL31616289 | 0.71 | ALDH1A1 (0.54) | ALDH1A1CYP3A4MAPK1CA1CA2 | |
| 1,4-Dichlorobenzene SCHEMBL11243685 | 0.71 | — | — | |
| 1,4-Dichlorobenzene SCHEMBL5191 | 0.71 | — | — | |
| SCHEMBL19259027 | 0.69 | ALDH1A1 (0.52) | ALDH1A1CYP3A4MAPK1LMNACYP2A6 | |
| SCHEMBL21875050 | 0.69 | TRPV4 (0.39) | IDO1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-101522611-B | Substituted phenylsulfur trifluoride and other similar fluorinating agents | UBE INDUSTRIES | 2013-07-17 | — | — | CN | claimed |
| US-8203003-B2 | 4-fluoropyrrolidine-2-carbonyl fluoride compounds and their preparative methods | UBE INDUSTRIES, LTD. (JP) | 2012-06-19 | — | — | US | claimed |
| US-20120083627-A1 | Method of Synthesis of Arylsulfur Trifluorides and Use as in situ Deoxofluorination Reagent | FLUOROTECH, LLC (US) | 2012-04-05 | — | — | US | claimed |
| US-20110275833-A1 | Novel 4-Fluoropyrrolidine-2-Carbonyl Fluoride Compounds and Their Preparative Methods | UBE INDUSTRIES, LTD. (JP) | 2011-11-10 | — | — | US | claimed |
| WO-2010081014-A1 | NOVEL 4-FLUOROPYRROLIDINE-2-CARBONYL FLUORIDE COMPOUNDS AND THEIR PREPARATIVE METHODS | IM&T RESEARCH, INC. (US) | 2010-07-15 | — | — | WO | claimed |
| US-20100174096-A1 | Methods for Production of Optically Active Fluoropyrrolidine Derivatives | IM&T RESEARCH, INC. (US) | 2010-07-08 | — | — | US | claimed |
| CN-101522611-A | Substituted phenylsulfur trifluoride and other similar fluorinating agents | IM & T RES INC (US) | 2009-09-02 | — | — | CN | claimed |
| EP-2046735-A2 | SUBSTITUTED PHENYLSULFUR TRIFLUORIDE AND OTHER LIKE FLUORINATING AGENTS | IM&T Research, Inc. (US) | 2009-04-15 | — | — | EP | claimed |
| US-7381846-B2 | E.g., Bis(2,6-dimethyl-3-chloro-4-tert-butylphenyl)disulfide and Bis(2,6-dimethyl-3,5-dichloro-4-tert-butylphenyl)disulfide; high yields; can be handled and stored in a safe manner; cost effective | IM&T RESEARCH, INC. (US) | 2008-06-03 | — | — | US | claimed |
| US-20080039660-A1 | E.g., Bis(2,6-dimethyl-3-chloro-4-tert-butylphenyl)disulfide and Bis(2,6-dimethyl-3,5-dichloro-4-tert-butylphenyl)disulfide; high yields; can be handled and stored in a safe manner; cost effective | IM&T RESEARCH, INC. (US) | 2008-02-14 | — | — | US | claimed |
| WO-2008013550-A1 | SUBSTITUTED PHENYLSULFUR TRIFLUORIDE AND OTHER LIKE FLUORINATING AGENTS | IM & T RESEARCH, INC. (US) | 2008-01-31 | — | — | WO | claimed |
| WO-2008014345-A2 | SUBSTITUTED PHENYLSULFUR TRIFLUORIDE AND OTHER LIKE FLUORINATING AGENTS | IM & T RESEARCH, INC. (US) | 2008-01-31 | — | — | WO | claimed |
| US-7265247-B1 | E.g., 2,6-dimethyl-4-tert-butylphenylsulfur trifluoride and 4-chlorophenylsulfur trifluoride; especially for fluorinating target compounds that have one or more oxygen or oxygen-containing groups that are replaced by the introduction of one or more fluorine atoms. | IM&T RESEARCH, INC. (US) | 2007-09-04 | — | — | US | claimed |
| WO-2025121400-A1 | PRODUCTION METHOD FOR FLUORINATED THIO GROUP–CONTAINING ARYL COMPOUND | ＡＧＣ株式会社 | 2025-06-12 | — | — | WO | disclosed |
| US-9365471-B2 | Substituted phenylsulfur trifluoride and other like fluorinating agents | UBE INDUSTRIES, LTD. (JP) | 2016-06-14 | — | — | US | disclosed |
| US-9365471-B2 | Substituted phenylsulfur trifluoride and other like fluorinating agents | UBE INDUSTRIES, LTD. (JP) | 2016-06-14 | — | — | US | disclosed |
| WO-2008013550-A1 | SUBSTITUTED PHENYLSULFUR TRIFLUORIDE AND OTHER LIKE FLUORINATING AGENTS | IM & T RESEARCH, INC. (US) | 2008-01-31 | — | — | WO | disclosed |
| US-7265247-B1 | E.g., 2,6-dimethyl-4-tert-butylphenylsulfur trifluoride and 4-chlorophenylsulfur trifluoride; especially for fluorinating target compounds that have one or more oxygen or oxygen-containing groups that are replaced by the introduction of one or more fluorine atoms. | IM&T RESEARCH, INC. (US) | 2007-09-04 | — | — | US | disclosed |
| US-7265247-B1 | E.g., 2,6-dimethyl-4-tert-butylphenylsulfur trifluoride and 4-chlorophenylsulfur trifluoride; especially for fluorinating target compounds that have one or more oxygen or oxygen-containing groups that are replaced by the introduction of one or more fluorine atoms. | IM&T RESEARCH, INC. (US) | 2007-09-04 | — | — | US | disclosed |
| US-7265247-B1 | E.g., 2,6-dimethyl-4-tert-butylphenylsulfur trifluoride and 4-chlorophenylsulfur trifluoride; especially for fluorinating target compounds that have one or more oxygen or oxygen-containing groups that are replaced by the introduction of one or more fluorine atoms. | IM&T RESEARCH, INC. (US) | 2007-09-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110275833-A1 | Novel 4-Fluoropyrrolidine-2-Carbonyl Fluoride Compounds and Their Preparative Methods | PFAS, AFF4, PAICS | ALDH1A1 916/4885CYP3A4 564/4885MAPK1 4405/4885 |
| US-20100174096-A1 | Methods for Production of Optically Active Fluoropyrrolidine Derivatives | QDPR, FDPS, DPYD | ALDH1A1 600/4885CYP3A4 114/4885MAPK1 4045/4885 |
| US-20120083627-A1 | Method of Synthesis of Arylsulfur Trifluorides and Use as in situ Deoxofluorination Reagent | AFF2, BRD2, AFF4 | ALDH1A1 92/4885CYP3A4 164/4885MAPK1 3391/4885 |
| US-20080039660-A1 | E.g., Bis(2,6-dimethyl-3-chloro-4-tert-butylphenyl)disulfide and Bis(2,6-dimethyl-3,5-dichloro-4-tert-butylphenyl)disulfide; high yields; can be handled and stored in a safe manner; cost effective | TST, DDT, ESD | ALDH1A1 2815/4885CYP3A4 318/4885MAPK1 4263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.