SCHEMBL8958887

SCHEMBL8958887

CC(C)c1cccc(C(C)C)c1S(=O)[O-].CC(C)c1cccc(C(C)C)c1S(=O)[O-].[Ca+2]

nearest known ligand 0.43

Known targets — ChEMBL curated mechanism

GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGRIN1GRIN2AGRIN2BGRIN2CGRIN2DGRIN3AGRIN3BHMGCRMMP1MMP13MMP7MMP8PTGS1PTGS2ileSpolrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO

The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 known ✓ P14867 3/20 0.43
GABRG2 known ✓ P18507 2/20 0.43
GABRB3 known ✓ P28472 2/20 0.43
GABRB2 known ✓ P47870 2/20 0.43
GABRB1 known ✓ P18505 1/20 0.43
PTGS1 known ✓ P23219 1/20 0.43
GABRA5 known ✓ P31644 1/20 0.43
GABRA3 known ✓ P34903 1/20 0.43
GABRA2 known ✓ P47869 1/20 0.43
GABRA4 known ✓ P48169 1/20 0.43
GABRA6 known ✓ Q16445 1/20 0.43
LMNA P02545 2/20 0.43
CYP3A4 P08684 2/20 0.43
CA1 P00915 2/20 0.43
CA2 P00918 2/20 0.43
FAAH O00519 1/20 0.43
CYP1A2 P05177 1/20 0.43
HPGD P15428 1/20 0.43
TSHR P16473 1/20 0.43
SLC6A2 P23975 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8959276 0.77 CYP3A4 (0.49) GABRA1GABRG2GABRB3LMNAGABRB2
SCHEMBL1021278 0.77 FABP4 (0.44) GABRA1GABRB2ALDH1A1
SCHEMBL22264128 0.76 GABRA1 (0.50) GABRA1GABRG2GABRB3LMNAGABRB2
SCHEMBL8958889 0.74 GABRA1 (0.48) GABRA1GABRG2GABRB3LMNAGABRB2
Potassium Ion SCHEMBL1022542 0.72 FABP4 (0.44) GABRA1GABRB2ALDH1A1
SCHEMBL346543 0.72 FABP4 (0.44) GABRA1GABRB2ALDH1A1
Lithium Ion SCHEMBL1033043 0.72 FABP4 (0.44) GABRA1GABRB2ALDH1A1
SCHEMBL199413 0.68 GABRA1 (0.57) GABRA1GABRG2GABRB3LMNAGABRB2
SCHEMBL31204330 0.67 GABRA1 (0.60) GABRA1GABRG2GABRB3LMNAGABRB2
SCHEMBL29140086 0.67 GABRA1 (0.44) GABRA1GABRG2GABRB3LMNAGABRB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5486544-A AROMATIC SULFINATE POLYMERIZATION CATALYST KURARAY CO., LTD. (JP) 1996-01-23 US disclosed
EP-0408357-B1 Polymerizable composition KURARAY CO (JP) 1994-06-01 EP disclosed
EP-0408357-A2 Polymerizable composition KURARAY CO., LTD. (JP) 1991-01-16 EP disclosed