SCHEMBL8959072

SCHEMBL8959072

CCCCCCCc1ccc(OCCNC(=O)C2CC2)c(Cl)c1

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 4/20 0.57
CNR2 P34972 4/20 0.57
KMT2A Q03164 3/20 0.50
MEN1 O00255 2/20 0.50
S1PR2 O95136 1/20 0.48
S1PR1 P21453 1/20 0.48
S1PR3 Q99500 1/20 0.48
LPAR2 Q9HBW0 1/20 0.48
SMN1; SMN2 Q16637 3/20 0.48
GLA P06280 1/20 0.48
ALDH1A1 P00352 1/20 0.47
ATM Q13315 1/20 0.46
CYP3A4 P08684 1/20 0.45
SPHK1 Q9NYA1 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8958965 0.84 KMT2A (0.48) CNR1CNR2KMT2AMEN1SMN1; SMN2
SCHEMBL8959043 0.82 KMT2A (0.46) CNR1CNR2KMT2AMEN1S1PR2
SCHEMBL8959057 0.79 LTA4H (0.52) KMT2AMEN1SMN1; SMN2ALDH1A1ATM
SCHEMBL8959095 0.78 KMT2A (0.43) CNR1CNR2KMT2AMEN1SMN1; SMN2
SCHEMBL8959097 0.78 KMT2A (0.42) CNR1CNR2KMT2AMEN1SMN1; SMN2
SCHEMBL9398654 0.76 SMN1; SMN2 (0.65) KMT2AMEN1S1PR2S1PR1S1PR3
SCHEMBL8959129 0.76 KMT2A (0.49) KMT2AMEN1SMN1; SMN2ALDH1A1
SCHEMBL8959018 0.75 KMT2A (0.48) CNR1CNR2KMT2AMEN1SMN1; SMN2
SCHEMBL9398842 0.75 SMN1; SMN2 (0.70) KMT2AMEN1S1PR2S1PR1S1PR3
SCHEMBL8959111 0.74 SMN1; SMN2 (0.74) KMT2AMEN1S1PR2S1PR1S1PR3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0514833-B1 Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL CO (JP) 1996-01-17 EP disclosed
US-5364966-A Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-11-15 US disclosed
US-5356930-A Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-10-18 US disclosed
EP-0514833-A2 Amide derivatives, their production processes and their compositions for the control of insect pests SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1992-11-25 EP disclosed