Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICMT | O60725 | 4/20 | 0.39 |
| ▸ | HTR3A | P46098 | 7/20 | 0.39 |
| ▸ | PLA2G4A | P47712 | 1/20 | 0.37 |
| ▸ | MMP1 | P03956 | 1/20 | 0.36 |
| ▸ | HTR2C | P28335 | 1/20 | 0.34 |
| ▸ | PER2 | O15055 | 1/20 | 0.34 |
| ▸ | CRY1 | Q16526 | 1/20 | 0.34 |
| ▸ | CRY2 | Q49AN0 | 1/20 | 0.34 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | CNR1 | P21554 | 1/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8959567 | 0.78 | HTR2A (0.36) | ICMTMMP1HTR2C | |
| SCHEMBL8959694 | 0.75 | HTR2C (0.58) | HTR2C | |
| Fumaric Acid SCHEMBL8959605 | 0.75 | HTR6 (0.48) | ICMTHTR3APLA2G4APOLBCNR1 | |
| Fumaric Acid SCHEMBL8959622 | 0.75 | HTR6 (0.48) | ICMTHTR3APLA2G4APOLBCNR1 | |
| SCHEMBL8959761 | 0.74 | TRPM5 (0.39) | HTR2CCNR1CNR2 | |
| SCHEMBL23927897 | 0.72 | HTR3A (0.36) | ICMTHTR3APLA2G4AHTR2CPER2 | |
| SCHEMBL29780354 | 0.72 | HTR3A (0.36) | ICMTHTR3APLA2G4AHTR2CPER2 | |
| SCHEMBL23927894 | 0.72 | HTR3A (0.36) | ICMTHTR3APLA2G4AHTR2CPER2 | |
| SCHEMBL8959690 | 0.72 | HTR6 (0.51) | ICMT | |
| SCHEMBL8959507 | 0.69 | HTR2C (0.60) | ICMTHTR2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5494928-A | FOR CENTRAL NERVOUS SYSTEM DISORDERS, BLOCKING SEROTONIN RECEPTORS, ANTIDEPRESSANTS | HOFFMANN-LA ROCHE INC. (US) | 1996-02-27 | — | — | US | disclosed |