Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPM5 | Q9NZQ8 | 13/20 | 0.38 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | HTR7 | P34969 | 1/20 | 0.32 |
| ▸ | PLA2G2A | P14555 | 3/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8959883 | 0.83 | TRPM5 (0.31) | TRPM5 | |
| SCHEMBL8959711 | 0.77 | HTR2C (0.45) | TRPM5 | |
| SCHEMBL8959761 | 0.76 | TRPM5 (0.39) | TRPM5PLA2G2A | |
| Fumaric Acid SCHEMBL8959767 | 0.74 | TRPM5 (0.47) | TRPM5HTR7 | |
| Fumaric Acid SCHEMBL8959756 | 0.74 | TRPM5 (0.47) | TRPM5HTR7 | |
| SCHEMBL7994539 | 0.73 | ALDH1A1 (0.38) | PLA2G2A | |
| Fumaric Acid SCHEMBL8959661 | 0.72 | HTR2C (0.45) | TRPM5HTR7 | |
| Fumaric Acid SCHEMBL8959671 | 0.72 | HTR2C (0.45) | TRPM5HTR7 | |
| SCHEMBL8959995 | 0.70 | TRPM5 (0.44) | TRPM5 | |
| SCHEMBL8959747 | 0.70 | AR (0.44) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5494928-A | FOR CENTRAL NERVOUS SYSTEM DISORDERS, BLOCKING SEROTONIN RECEPTORS, ANTIDEPRESSANTS | HOFFMANN-LA ROCHE INC. (US) | 1996-02-27 | — | — | US | disclosed |