SCHEMBL8960291

SCHEMBL8960291

CC(C)n1c(=O)sc2cc(F)c(-n3cnc(C(F)(F)F)cc3=O)cc21

nearest known ligand 0.33

Predicted protein targets (top 3)

geneUniProtsupporting neighboursconfidence
GRIA1 P42261 1/20 0.33
CNR2 P34972 1/20 0.31
KARS1 Q15046 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8960446 0.81 CNR2 (0.30) CNR2
SCHEMBL9423829 0.74 CNR2 (0.31) CNR2
SCHEMBL9032574 0.72 BCAT1 (0.46)
SCHEMBL9478152 0.70 CNR2 (0.32) CNR2
SCHEMBL8960424 0.69 PPOX (0.33)
SCHEMBL7085889 0.67 TRPV4 (0.37)
SCHEMBL8960336 0.66 POLB (0.33)
SCHEMBL9423820 0.65 KARS1 (0.30) KARS1
SCHEMBL16830345 0.65 PKM (0.34)
SCHEMBL11783513 0.64 PTGS2 (0.40) GRIA1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5532208-A HERBICIDES SUMITOMO CHEMICAL CO., LTD. (JP) 1996-07-02 US disclosed
US-5366955-A HERBICIDES SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-11-22 US disclosed
EP-0568041-A1 Pyrimidone derivatives and their use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1993-11-03 EP disclosed