SCHEMBL8961903

SCHEMBL8961903

C=CC[SiH](Oc1ccccc1)[C](C)C=C

nearest known ligand 0.35

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.35
SMN1; SMN2 Q16637 2/20 0.32
KDM4E B2RXH2 1/20 0.32
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32
TGM2 P21980 1/20 0.31
MMP9 P14780 1/20 0.31
GLA P06280 1/20 0.31
GAA P10253 1/20 0.31
HTT P42858 1/20 0.31
RAB9A P51151 1/20 0.31
LMNA P02545 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1782417 0.76 THRB (0.38) THRBSMN1; SMN2KDM4EMEN1KMT2A
SCHEMBL1493063 0.63 ALDH1A1 (0.35) THRBSMN1; SMN2KDM4EMEN1KMT2A
SCHEMBL5412046 0.62 PAX8 (0.40) LMNA
Diphenylether SCHEMBL28276171 0.62 LTA4H (0.55) SMN1; SMN2TGM2GLAGAAHTT
SCHEMBL2168155 0.62 CYP2C19 (0.36) THRBSMN1; SMN2KDM4EMEN1KMT2A
SCHEMBL22654269 0.62 CYP3A4 (0.36) THRBSMN1; SMN2KDM4EMEN1KMT2A
SCHEMBL1781213 0.62 ALDH1A1 (0.39) THRBSMN1; SMN2KDM4EMEN1KMT2A
SCHEMBL2170644 0.62 CA4 (0.34) LMNA
SCHEMBL28334373 0.61 NPC1 (0.47) THRBSMN1; SMN2KDM4EMEN1KMT2A
SCHEMBL1493065 0.61 AOC3 (0.32) THRBSMN1; SMN2KDM4EMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0564275-B1 Antifouling paint NIPPON PAINT CO LTD (JP) 1996-01-31 EP disclosed
US-5332431-A Alkylphenoxy group containing organosilicon compound NIPPON PAINT CO., LTD. (JP) 1994-07-26 US disclosed
EP-0564275-A1 Antifouling paint NIPPON PAINT CO., LTD. (JP) 1993-10-06 EP disclosed