Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | GPR119 | Q8TDV5 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | RAB9A | P51151 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11679467 | 0.82 | MMP8 (0.39) | MEN1KMT2AMMP8ALDH1A1SMN1; SMN2 | |
| SCHEMBL29700091 | 0.80 | MEN1 (0.55) | MEN1KMT2AALDH1A1SMN1; SMN2GAA | |
| SCHEMBL896714 | 0.79 | ALDH1A1 (0.47) | MEN1KMT2AMMP8ALDH1A1SMN1; SMN2 | |
| SCHEMBL17487291 | 0.75 | ALDH1A1 (0.53) | MEN1KMT2AMMP8ALDH1A1SMN1; SMN2 | |
| SCHEMBL23611731 | 0.75 | BRD4 (0.49) | ALDH1A1TSHRMAPTMAPK1CYP1A2 | |
| SCHEMBL4924785 | 0.75 | ALDH1A1 (0.49) | MEN1KMT2AMMP8ALDH1A1SMN1; SMN2 | |
| SCHEMBL25759221 | 0.73 | MEN1 (0.40) | MEN1KMT2AMMP8ALDH1A1SMN1; SMN2 | |
| SCHEMBL896209 | 0.72 | MEN1 (0.56) | MEN1KMT2AALDH1A1TSHRMAPT | |
| SCHEMBL896383 | 0.72 | ALDH1A1 (0.50) | MEN1KMT2AMMP8ALDH1A1SMN1; SMN2 | |
| SCHEMBL5772792 | 0.72 | MEN1 (0.44) | MEN1KMT2AMMP8ALDH1A1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107531648-B | Herbicidal compounds | 先正达参股股份有限公司 | 2021-07-13 | — | — | CN | disclosed |
| US-10385063-B2 | Herbicidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2019-08-20 | — | — | US | disclosed |
| US-10385063-B2 | Herbicidal compounds | SYNGENTA PARTICIPATIONS AG (CH) | 2019-08-20 | — | — | US | disclosed |
| EP-3288924-B1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-04-03 | — | — | EP | disclosed |
| EP-3288924-B1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2019-04-03 | — | — | EP | disclosed |
| US-20180111948-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-04-26 | — | — | US | disclosed |
| US-20180111948-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2018-04-26 | — | — | US | disclosed |
| EP-3288924-A1 | HERBICIDAL COMPOUNDS | Syngenta Participations AG (CH) | 2018-03-07 | — | — | EP | disclosed |
| WO-2016174073-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-11-03 | — | — | WO | disclosed |
| WO-2016174073-A1 | HERBICIDAL COMPOUNDS | SYNGENTA PARTICIPATIONS AG (CH) | 2016-11-03 | — | — | WO | disclosed |
| US-8258136-B2 | Pyridazine compound and use thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-09-04 | — | — | US | disclosed |
| WO-2012062531-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2012-05-18 | — | — | WO | disclosed |
| WO-2012062531-A1 | HERBICIDAL COMPOUNDS | SYNGENTA LIMITED (GB) | 2012-05-18 | — | — | WO | disclosed |
| US-20120083605-A1 | PYRIDAZINE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED | 2012-04-05 | — | — | US | disclosed |
| US-20120083605-A1 | PYRIDAZINE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED | 2012-04-05 | — | — | US | disclosed |
| EP-1958946-B1 | PYRIDAZINE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2011-02-23 | — | — | EP | disclosed |
| EP-1958946-B1 | PYRIDAZINE COMPOUND AND USE THEREOF | SUMITOMO CHEMICAL CO (JP) | 2011-02-23 | — | — | EP | disclosed |
| US-20090275589-A1 | Pyridazine Compound and Use Thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2009-11-05 | — | — | US | disclosed |
| CN-101326176-A | Pyridazine compound and use thereof | SUMITOMO CHEMICAL CO (JP) | 2008-12-17 | — | — | CN | disclosed |
| EP-1958946-A1 | PYRIDAZINE COMPOUND AND USE THEREOF | Sumitomo Chemical Company, Limited (JP) | 2008-08-20 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10385063-B2 | Herbicidal compounds | DDT, DAO, HPD | MEN1 4699/4885KMT2A 1737/4885MMP8 3535/4885 |
| US-20180111948-A1 | HERBICIDAL COMPOUNDS | DDT, DAO, HPD | MEN1 4693/4885KMT2A 1734/4885MMP8 3550/4885 |
| US-20120083605-A1 | PYRIDAZINE COMPOUND AND USE THEREOF | PLPBP, PNPO, PDXK | MEN1 3015/4885KMT2A 1894/4885MMP8 4427/4885 |
| US-20090275589-A1 | Pyridazine Compound and Use Thereof | PLPBP, PNPO, PDXK | MEN1 3015/4885KMT2A 1894/4885MMP8 4427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.