Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 2/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.35 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.35 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | CHEK2 | O96017 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.32 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.32 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | KHK | P50053 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 2/20 | 0.31 |
| ▸ | HTR1D | P28221 | 2/20 | 0.31 |
| ▸ | HTR7 | P34969 | 2/20 | 0.31 |
| ▸ | HTR2B | P41595 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8964138 | 0.91 | SLC6A4 (0.38) | TACR1ADRB1PRMT5PIN1CHEK2 | |
| SCHEMBL8963580 | 0.90 | PRMT5 (0.40) | TACR1PRMT5MEN1KMT2ACYP3A4 | |
| Hydrochloric Acid SCHEMBL8963783 | 0.89 | PRMT5 (0.40) | TACR1PRMT5MEN1KMT2ACYP3A4 | |
| SCHEMBL8963691 | 0.89 | TACR1 (0.34) | TACR1PRMT5CHEK2OPRD1 | |
| SCHEMBL8963532 | 0.89 | SLC6A2 (0.41) | TACR1ADRB1PRMT5PIN1CYP3A4 | |
| SCHEMBL8964088 | 0.89 | OPRD1 (0.37) | ADRB1PRMT5MEN1KMT2ACHEK2 | |
| SCHEMBL8963860 | 0.87 | PIN1 (0.43) | TACR1ADRB1PRMT5PIN1MEN1 | |
| SCHEMBL8963679 | 0.84 | MEN1 (0.42) | PRMT5PIN1MEN1KMT2AOPRD1 | |
| SCHEMBL8963516 | 0.84 | CHEK2 (0.42) | ADRB1PRMT5CHEK2OPRD1OPRM1 | |
| SCHEMBL8963637 | 0.84 | MAPK13 (0.37) | PRMT5CHEK2MAPK14OPRD1OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5514800-A | CALCIUM CHANNEL BLOCKERS, CEREBRAL ISCHEMIA | SYNTEX PHARMACEUTICALS, LTD. (GB) | 1996-05-07 | — | — | US | disclosed |