SCHEMBL8965288

SCHEMBL8965288

CCOC(C)Oc1ccc(C=C(C=Cc2ccc(C)cc2)C(O)=Cc2ccccc2)cc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LTB4R Q15722 1/20 0.39
LTB4R2 Q9NPC1 1/20 0.39
MAOB P27338 2/20 0.39
RELA Q04206 1/20 0.38
MAPT P10636 2/20 0.37
KMT2A Q03164 2/20 0.37
NPC1 O15118 2/20 0.37
MAOA P21397 1/20 0.37
RAB9A P51151 1/20 0.37
TRPM8 Q7Z2W7 2/20 0.36
CYP1B1 Q16678 1/20 0.36
ALDH1A1 P00352 1/20 0.36
CYP3A4 P08684 1/20 0.36
HPGD P15428 1/20 0.36
EGFR P00533 1/20 0.35
PPARG P37231 1/20 0.34
PPARA Q07869 1/20 0.34
NR1H4 Q96RI1 1/20 0.34
MEN1 O00255 1/20 0.34
MTOR P42345 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8898528 0.82 LTB4R (0.44) LTB4RLTB4R2MAOBRELAMAPT
SCHEMBL27224303 0.79 RELA (0.59) RELAMAPTKMT2ANPC1RAB9A
SCHEMBL7199294 0.78 LTB4R (0.41) LTB4RLTB4R2MAOBRELAMAPT
SCHEMBL3838358 0.78 CA12 (0.43) MAOBMAPTKMT2AMAOARAB9A
SCHEMBL3842067 0.78 LTB4R (0.41) LTB4RLTB4R2MAOBRELAMAPT
SCHEMBL6280731 0.73 RELA (0.41) MAOBRELAALDH1A1NR1H4
SCHEMBL14009524 0.73 LMNA (0.44) MAPTKMT2ATRPM8ALDH1A1CYP3A4
SCHEMBL8898532 0.72 RELA (0.43) LTB4RLTB4R2RELAMAPTKMT2A
SCHEMBL4965564 0.70 LTB4R (0.39) LTB4RLTB4R2MAOBMAPTKMT2A
SCHEMBL8897477 0.69 TRPA1 (0.45) LTB4RLTB4R2MAOBRELAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5558971-A HYDROXYSTYRENE POLYMER DERIVATIVES, PHOTOACID GENERATOR WAKO PURE CHEMICAL INDUSTRIES, LTD. (JP) 1996-09-24 US disclosed