Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 1/20 | 0.47 |
| ▸ | F12 | P00748 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.46 |
| ▸ | RAD51 | Q06609 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 1/20 | 0.45 |
| ▸ | MIF | P14174 | 1/20 | 0.45 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.44 |
| ▸ | CDK2 | P24941 | 1/20 | 0.44 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | GFER | P55789 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15559316 | 0.80 | MGLL (0.46) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL5226512 | 0.78 | MMP1 (0.40) | ALDH1A1MAPTKMT2AMEN1CYP1A2 | |
| SCHEMBL151398 | 0.76 | NPC1 (0.50) | F2F12KMT2AMEN1CDK2 | |
| SCHEMBL13411809 | 0.75 | ALDH1A1 (0.47) | F2F12ALDH1A1MAPTRAD51 | |
| SCHEMBL13715672 | 0.74 | SMN1; SMN2 (0.57) | MAPTKMT2AMEN1CDK2HTT | |
| SCHEMBL1502066 | 0.72 | HPGD (0.43) | ALDH1A1MAPTKMT2AMEN1KDM4E | |
| SCHEMBL4552789 | 0.72 | NPC1 (0.47) | F2F12KMT2AMEN1CDK2 | |
| SCHEMBL13411808 | 0.72 | ALDH1A1 (0.46) | F2F12ALDH1A1MAPTRAD51 | |
| SCHEMBL2528923 | 0.72 | ALDH1A1 (0.54) | ALDH1A1MAPTKMT2AMEN1CDK2 | |
| SCHEMBL10934369 | 0.72 | BTK (0.47) | MAPTKMT2AMEN1POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120083476-A1 | HETEROARYL-SUBSTITUTED SPIROCYCLIC DIAMINE UREA MODULATORS OF FATTY ACID AMIDE HYDROLASE | JANSSEN PHARMACEUTICA NV (BE) | 2012-04-05 | — | — | US | disclosed |
| US-20120083476-A1 | HETEROARYL-SUBSTITUTED SPIROCYCLIC DIAMINE UREA MODULATORS OF FATTY ACID AMIDE HYDROLASE | JANSSEN PHARMACEUTICA NV (BE) | 2012-04-05 | — | — | US | disclosed |
| US-20120083476-A1 | HETEROARYL-SUBSTITUTED SPIROCYCLIC DIAMINE UREA MODULATORS OF FATTY ACID AMIDE HYDROLASE | JANSSEN PHARMACEUTICA NV (BE) | 2012-04-05 | — | — | US | disclosed |
| WO-2010141817-A1 | HETEROARYL-SUBSTITUTED SPIROCYCLIC DIAMINE UREA MODULATORS OF FATTY ACID AMIDE HYDROLASE | JANSSEN PHARMACEUTICA NV (BE) | 2010-12-09 | — | — | WO | disclosed |
| WO-2010141817-A1 | HETEROARYL-SUBSTITUTED SPIROCYCLIC DIAMINE UREA MODULATORS OF FATTY ACID AMIDE HYDROLASE | JANSSEN PHARMACEUTICA NV (BE) | 2010-12-09 | — | — | WO | disclosed |
| US-20100075500-A1 | Metal polishing slurry and chemical mechanical polishing method | FUJIFILM CORPORATION (JP) | 2010-03-25 | — | — | US | disclosed |
| US-20100075500-A1 | Metal polishing slurry and chemical mechanical polishing method | FUJIFILM CORPORATION (JP) | 2010-03-25 | — | — | US | disclosed |
| US-20090203215-A1 | METAL POLISHING SLURRY AND CHEMICAL MECHANICAL POLISHING METHOD | FUJIFILM CORPORATION (JP) | 2009-08-13 | — | — | US | disclosed |
| US-20090203215-A1 | METAL POLISHING SLURRY AND CHEMICAL MECHANICAL POLISHING METHOD | FUJIFILM CORPORATION (JP) | 2009-08-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120083476-A1 | HETEROARYL-SUBSTITUTED SPIROCYCLIC DIAMINE UREA MODULATORS OF FATTY ACID AMIDE HYDROLASE | FAAH, FAAH2, DBH | F2 877/4885F12 3739/4885ALDH1A1 709/4885 |
| US-20100075500-A1 | Metal polishing slurry and chemical mechanical polishing method | NOX1, NOXO1, PIEZO1 | F2 1192/4885F12 62/4885ALDH1A1 2991/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.