Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | CTSL | P07711 | 3/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | DDOST | P39656 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 2/20 | 0.33 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | PSMB11 | A5LHX3 | 1/20 | 0.32 |
| ▸ | PSMA7 | O14818 | 1/20 | 0.32 |
| ▸ | PSMB1 | P20618 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL644954 | 0.83 | OPRD1 (0.39) | SMN1; SMN2HPGDBACE1 | |
| SCHEMBL10492892 | 0.77 | MMP2 (0.49) | — | |
| SCHEMBL8330156 | 0.72 | MEN1 (0.39) | SMN1; SMN2HPGDALDH1A1MEN1LMNA | |
| SCHEMBL8351160 | 0.72 | MMP1 (0.45) | BACE1MEN1MAPTKMT2APSMB11 | |
| SCHEMBL18507619 | 0.71 | ALDH1A1 (0.39) | SMN1; SMN2HPGDBACE1ALDH1A1MEN1 | |
| SCHEMBL614030 | 0.71 | TDP1 (0.36) | SMN1; SMN2HPGDALDH1A1MEN1MAPT | |
| SCHEMBL10492870 | 0.71 | REN (0.46) | BACE1 | |
| SCHEMBL9839725 | 0.69 | MEN1 (0.44) | SMN1; SMN2HPGDALDH1A1MEN1LMNA | |
| SCHEMBL14968851 | 0.67 | KDR (0.39) | BACE1MMP9 | |
| SCHEMBL468592 | 0.67 | MEN1 (0.43) | SMN1; SMN2HPGDALDH1A1MEN1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516685-A | AND DNA MOLECULE ENCODING POLYPEPTIDE OF SPCIFIED AMINO ACID SEQUENCE | AMGEN INC. (US) | 1996-05-14 | — | — | US | disclosed |
| EP-0546156-A4 | ISOLATION AND CHARACTERIZATION OF A NOVEL PROTEASE FROM STREPTOMYCES LIVIDANS | — | 1993-06-30 | — | — | EP | disclosed |
| EP-0546156-A1 | ISOLATION AND CHARACTERIZATION OF A NOVEL PROTEASE FROM STREPTOMYCES LIVIDANS | AMGEN INC. (US) | 1993-06-16 | — | — | EP | disclosed |
| WO-1993000925-A1 | ISOLATION AND CHARACTERIZATION OF A NOVEL PROTEASE FROM STREPTOMYCES LIVIDANS | AMGEN INC. (US) | 1993-01-21 | — | — | WO | disclosed |