Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP11B1 | P15538 | 1/20 | 0.54 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 5/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | ATM | Q13315 | 1/20 | 0.53 |
| ▸ | AHR | P35869 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.49 |
| ▸ | RAB9A | P51151 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.48 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.48 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.48 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.47 |
| ▸ | BRAF | P15056 | 1/20 | 0.47 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8970501 | 0.87 | CXCR1 (0.45) | CYP11B1CYP11B2MEN1KMT2AMAPT | |
| SCHEMBL8968747 | 0.85 | CXCR1 (0.49) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL8968160 | 0.85 | CXCR2 (0.65) | MEN1KMT2AMAPTLMNAHTT | |
| SCHEMBL8968203 | 0.84 | ABCC9 (0.45) | CYP11B1CYP11B2MEN1KMT2AMAPT | |
| SCHEMBL8968199 | 0.84 | ABCC9 (0.45) | CYP11B1CYP11B2MEN1KMT2AMAPT | |
| SCHEMBL8968172 | 0.81 | RAB9A (0.52) | MEN1KMT2AMAPTHTTNPC1 | |
| SCHEMBL8968849 | 0.81 | CYP11B1 (0.53) | CYP11B1CYP11B2MEN1KMT2AMAPT | |
| SCHEMBL17079612 | 0.80 | MEN1 (0.67) | CYP11B1CYP11B2MEN1KMT2AMAPT | |
| SCHEMBL8968177 | 0.78 | NPC1 (0.54) | CYP11B1CYP11B2MEN1KMT2AMAPT | |
| SCHEMBL8969388 | 0.78 | HSD17B10 (0.53) | CYP11B1CYP11B2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5547966-A | Aryl urea and related compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-08-20 | — | — | US | claimed |
| EP-0656350-A1 | Biaryl urea and related compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-06-07 | — | — | EP | claimed |
| US-5547966-A | Aryl urea and related compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-08-20 | — | — | US | disclosed |
| EP-0656350-A1 | Biaryl urea and related compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-06-07 | — | — | EP | disclosed |