Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR3 | P51677 | 8/20 | 0.47 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | NAMPT | P43490 | 4/20 | 0.42 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.42 |
| ▸ | CXCR2 | P25025 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.41 |
| ▸ | P2RY1 | P47900 | 1/20 | 0.41 |
| ▸ | FAAH | O00519 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8968160 | 0.78 | CXCR2 (0.65) | CXCR1CXCR2P2RY1ALDH1A1 | |
| SCHEMBL8970592 | 0.77 | CXCR1 (0.47) | CCR3CXCR1CXCR2ALDH1A1 | |
| SCHEMBL8968156 | 0.74 | GAA (0.49) | CXCR1CXCR2ALDH1A1 | |
| SCHEMBL9757428 | 0.74 | MEN1 (0.56) | NAMPTABCB1ALDH1A1 | |
| SCHEMBL8968747 | 0.70 | CXCR1 (0.49) | NAMPTCXCR1CXCR2ALDH1A1 | |
| SCHEMBL8970501 | 0.69 | CXCR1 (0.45) | ARCXCR1CXCR2P2RY1ALDH1A1 | |
| SCHEMBL8968218 | 0.69 | CYP11B1 (0.54) | CXCR1CXCR2ALDH1A1 | |
| SCHEMBL19035635 | 0.68 | DRD3 (0.60) | ALDH1A1 | |
| SCHEMBL8120677 | 0.67 | SIGMAR1 (0.52) | ABCB1ALDH1A1 | |
| SCHEMBL8970479 | 0.67 | ALOX12 (0.68) | ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0656350-A1 | Biaryl urea and related compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-06-07 | — | — | EP | claimed |
| US-5547966-A | Aryl urea and related compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-08-20 | — | — | US | disclosed |
| EP-0656350-A1 | Biaryl urea and related compounds | BRISTOL-MYERS SQUIBB COMPANY (US) | 1995-06-07 | — | — | EP | disclosed |