Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 11/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.35 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.35 |
| ▸ | BCHE | P06276 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8969440 | 0.86 | ACHE (0.38) | ACHEALDH1A1KDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL8968687 | 0.81 | MAOA (0.34) | ACHE | |
| SCHEMBL8968531 | 0.80 | ACHE (0.33) | ACHE | |
| SCHEMBL8968545 | 0.79 | ACHE (0.39) | ACHEALDH1A1KDM4EHSD17B10SMN1; SMN2 | |
| SCHEMBL8969227 | 0.78 | ACHE (0.49) | ACHE | |
| SCHEMBL8968801 | 0.77 | ACHE (0.36) | ACHEPDE3BPDE3ABCHE | |
| SCHEMBL8969764 | 0.75 | PDE3B (0.34) | PDE3BPDE3A | |
| SCHEMBL8969504 | 0.73 | ACHE (0.40) | ACHEPDE3BPDE3A | |
| SCHEMBL8968874 | 0.70 | CTSD (0.41) | ALDH1A1KDM4ESMN1; SMN2 | |
| SCHEMBL8969419 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5486512-A | LEARNING ENHANCEMENT | WARNER-LAMBERT COMPANY (US) | 1996-01-23 | — | — | US | disclosed |
| WO-1993003034-A1 | QUINAZOLINE DERIVATIVES AS ACETYLCHOLINESTERASE INHIBITORS | WARNER-LAMBERT COMPANY (US) | 1993-02-18 | — | — | WO | disclosed |