SCHEMBL8973835

SCHEMBL8973835

COc1cc2nn(-c3ccc(O)cc3O)nc2cc1OC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAOB P27338 1/20 0.46
GAA P10253 3/20 0.43
POLB P06746 3/20 0.43
MEN1 O00255 2/20 0.43
KMT2A Q03164 2/20 0.43
RAB9A P51151 3/20 0.40
ALDH1A1 P00352 2/20 0.40
MAPT P10636 1/20 0.40
SMN1; SMN2 Q16637 1/20 0.40
PDGFRB P09619 1/20 0.40
PDGFRA P16234 1/20 0.40
RET P07949 2/20 0.39
KDR P35968 2/20 0.39
KIF5B P33176 1/20 0.39
NPC1 O15118 2/20 0.37
LMNA P02545 2/20 0.37
ESR1 P03372 2/20 0.37
ESR2 Q92731 1/20 0.37
NQO2 P16083 1/20 0.37
GAK O14976 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29602187 0.83 TYR (0.44) GAAPOLBMEN1KMT2ARAB9A
SCHEMBL8973631 0.83 TYR (0.44) GAAPOLBMEN1KMT2ARAB9A
SCHEMBL28556638 0.83 NPC1 (0.40) POLBMEN1KMT2ARAB9ANPC1
SCHEMBL11375525 0.81 RAB9A (0.44) GAAMEN1KMT2ARAB9AALDH1A1
SCHEMBL17201891 0.81 NPC1 (0.42) POLBMEN1KMT2ARAB9AALDH1A1
SCHEMBL45835 0.78 NPC1 (0.54) GAAPOLBMEN1KMT2ARAB9A
SCHEMBL9010899 0.77 NPC1 (0.55) GAAPOLBMEN1KMT2ARAB9A
SCHEMBL2801293 0.74 NPC1 (0.37) GAAPOLBMEN1KMT2ARAB9A
SCHEMBL29602456 0.74 AMY1A (0.42) MAOBMEN1KMT2ARAB9ANPC1
SCHEMBL7783973 0.74 AMY1A (0.42) MAOBMEN1KMT2ARAB9ANPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5585228-A Benzotriazole based UV absorbing compounds and photographic elements containing them EASTMAN KODAK COMPANY (US) 1996-12-17 US disclosed
US-5554759-A Benzotriazole based uv absorbing monomers and photographic elements containg polymers formed them EASTMAN KODAK COMPANY (US) 1996-09-10 US disclosed
EP-0717313-A1 Benzotriazole based UV absorbing compounds and photographic elements containing them EASTMAN KODAK COMPANY (US) 1996-06-19 EP disclosed
EP-0704754-A2 Benzotriazole based UV absorbing monomers and photographic elements containing polymers formed from them EASTMAN KODAK COMPANY (US) 1996-04-03 EP disclosed
US-5455152-A Maintain whiteness provided by optical brighteners EASTMAN KODAK COMPANY (US) 1995-10-03 US disclosed