Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Potassium Ion. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | DUSP5 | Q16690 | 1/20 | 0.35 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.35 |
| ▸ | F2 | P00734 | 3/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.34 |
| ▸ | CA1 | P00915 | 3/20 | 0.33 |
| ▸ | CA2 | P00918 | 3/20 | 0.33 |
| ▸ | MMP1 | P03956 | 2/20 | 0.33 |
| ▸ | MMP2 | P08253 | 2/20 | 0.33 |
| ▸ | MMP9 | P14780 | 2/20 | 0.33 |
| ▸ | MMP8 | P22894 | 2/20 | 0.33 |
| ▸ | MMP13 | P45452 | 2/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 2/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7718865 | 0.96 | KDM4E (0.42) | KDM4EALDH1A1HPGDDUSP5NR4A1 | |
| SCHEMBL17200750 | 0.96 | KDM4E (0.38) | KDM4EALDH1A1HPGDDUSP5NR4A1 | |
| Potassium Ion SCHEMBL9402886 | 0.85 | KDM4E (0.38) | KDM4EALDH1A1HPGDNR4A1F2 | |
| Potassium Ion SCHEMBL3769154 | 0.82 | ALDH1A1 (0.47) | KDM4EALDH1A1HPGDF2PRSS1 | |
| SCHEMBL7517747 | 0.82 | THRB (0.38) | KDM4EALDH1A1HPGDDUSP5NR4A1 | |
| SCHEMBL7088482 | 0.81 | KDM4E (0.38) | KDM4EALDH1A1HPGDNR4A1F2 | |
| SCHEMBL7553184 | 0.81 | KDM4E (0.38) | KDM4EALDH1A1HPGDNR4A1F2 | |
| SCHEMBL11143108 | 0.81 | KDM4E (0.38) | KDM4EALDH1A1HPGDNR4A1F2 | |
| SCHEMBL3170816 | 0.81 | KDM4E (0.38) | KDM4EALDH1A1HPGDNR4A1F2 | |
| SCHEMBL5964378 | 0.81 | KDM4E (0.38) | KDM4EALDH1A1HPGDNR4A1F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5530093-A | SOIL RELEASE AGENTS, ANTISTATIC AGENTS FOR TEXTILE FINISHING | CASSELLA AKTIENGESELLSCHAFT (DE) | 1996-06-25 | — | — | US | disclosed |