Known targets — ChEMBL curated mechanism
ABCC8ACEADORA1ADORA2AADORA2BADORA3ALDH5A1ALOX5ALOX5APATP4AATP4BBRAFCA1CA12CA2CA4CYSLTR1DHFRDPEP1EDNRAEDNRBESR2F10FDPSFGF1GABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTGNRHRGSC1HMGCRIMPDH1IMPDH2KCNJ11LY96NOD2NR3C1NS3NS4ANS5bP2RY1P2RY12P2RY2P2RY4P2RY6PBP2XPDE3APDE3BPDE4APDE4BPDE4CPDE4DPDK1PDK2PDK3PDK4PPARGPPATPTGIRPTGS1PTGS2RAF1RYR1RYR3SCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASERPINC1SLC12A1SLC12A3SYKTHRATHRBTLR3TLR4TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8TYMSVKORC1XDHblablaIMP-1blaOXA-33blaOXA-58blaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAfolPfolP1ftsIfusAgaggyrAgyrBmecAmrcAmrcBmrdApbp1apbp1bpbp2pbp2apbp2bpbp3pbp4pbpApbpBpbpCpbpFpolponBrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpoArpoBrpoCrpoZrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY4 known ✓ | P51582 | 1/20 | 0.34 |
| ▸ | P2RY12 known ✓ | Q9H244 | 1/20 | 0.34 |
| ▸ | CA2 known ✓ | P00918 | 4/20 | 0.33 |
| ▸ | CA1 known ✓ | P00915 | 3/20 | 0.33 |
| ▸ | CA4 known ✓ | P22748 | 1/20 | 0.33 |
| ▸ | PTGS1 known ✓ | P23219 | 1/20 | 0.32 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | DUSP5 | Q16690 | 1/20 | 0.38 |
| ▸ | PKLR | P30613 | 3/20 | 0.34 |
| ▸ | F2 | P00734 | 2/20 | 0.34 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.34 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.34 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.34 |
| ▸ | MMP1 | P03956 | 1/20 | 0.33 |
| ▸ | MMP2 | P08253 | 1/20 | 0.33 |
| ▸ | MMP9 | P14780 | 1/20 | 0.33 |
| ▸ | MMP8 | P22894 | 1/20 | 0.33 |
| ▸ | MMP13 | P45452 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Potassium Ion SCHEMBL8980356 | 0.96 | KDM4E (0.38) | KDM4EALDH1A1HPGDDUSP5PKLR | |
| SCHEMBL17200750 | 0.96 | KDM4E (0.38) | KDM4EALDH1A1HPGDDUSP5PKLR | |
| SCHEMBL3183959 | 0.85 | KDM4E (0.42) | KDM4EALDH1A1HPGDPKLRF2 | |
| SCHEMBL7517747 | 0.85 | THRB (0.38) | KDM4EALDH1A1HPGDDUSP5ALOX15 | |
| SCHEMBL979896 | 0.82 | ALDH1A1 (0.52) | KDM4EALDH1A1HPGDDUSP5PKLR | |
| SCHEMBL3170816 | 0.81 | KDM4E (0.38) | KDM4EALDH1A1HPGDF2PRSS1 | |
| SCHEMBL7088482 | 0.81 | KDM4E (0.38) | KDM4EALDH1A1HPGDF2PRSS1 | |
| SCHEMBL5964378 | 0.81 | KDM4E (0.38) | KDM4EALDH1A1HPGDF2PRSS1 | |
| SCHEMBL11143108 | 0.81 | KDM4E (0.38) | KDM4EALDH1A1HPGDF2PRSS1 | |
| SCHEMBL7553184 | 0.81 | KDM4E (0.38) | KDM4EALDH1A1HPGDF2PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4507468-A | Method for purifying polyphenylene sulfide | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1985-03-26 | — | — | US | claimed |
| CN-117186388-B | Nylon composite material and preparation method and application thereof | 中山海明中科新材料有限公司 | 2024-04-19 | — | — | CN | disclosed |
| CN-117186388-A | Nylon composite material and preparation method and application thereof | 中山海明中科新材料有限公司 | 2023-12-08 | — | — | CN | disclosed |
| US-6383415-B1 | Methods of fabrication of cross-linked electrically conductive polymers and precursors thereof | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2002-05-07 | — | — | US | disclosed |
| US-6193909-B1 | CROSSLINKED POLYMER PRECURSOR HAVING HYDROXYALKYL MOIETIES PROVIDING CROSSLINKING AND SOLVENT SOLVATING FUNCTIONALITY; THERMAL AND ENVIRONMENTAL STABILITY, SOLVENT RESISTANCE AND NONDIFFUSION OF DOPANT | INTERNATIONAL BUSINESS MACHINES CORPORATION | 2001-02-27 | — | — | US | disclosed |
| US-6030550-A | DOPANTS AND SUBSTITUENTS HAVING PENDANT CROSSLINKABLE FUNCTIONALITY ARE USED TO FORM A STABLE, CROSSLINKED, ELECTROCONDUCTIVE, DOPED POLYMER; INTERPENETRATING POLYMER NETWORKS; HEAT AND CHEMICAL RESISTANCE; WEATHERPROOFING | INTERNATIONAL BUSINESS MACHINES CORPORATION (US) | 2000-02-29 | — | — | US | disclosed |
| US-4507468-A | Method for purifying polyphenylene sulfide | DAINIPPON INK AND CHEMICALS, INC. (JP) | 1985-03-26 | — | — | US | disclosed |