Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | MAOB | P27338 | 3/20 | 0.48 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.42 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8980593 | 0.87 | MAOB (0.49) | L3MBTL1RAB9AMAOBMAOASMN1; SMN2 | |
| SCHEMBL8980579 | 0.84 | TSHR (0.53) | L3MBTL1MAOBSMN1; SMN2HTTCYP3A4 | |
| SCHEMBL8876362 | 0.83 | TP53 (0.48) | L3MBTL1RAB9ASMN1; SMN2MAPTLMNA | |
| SCHEMBL8980925 | 0.81 | ALDH1A1 (0.60) | L3MBTL1RAB9ASMN1; SMN2MAPTLMNA | |
| SCHEMBL28877532 | 0.74 | ALDH1A1 (0.56) | L3MBTL1MAOBLMNAHTTCYP3A4 | |
| SCHEMBL10600006 | 0.73 | RAB9A (0.81) | L3MBTL1RAB9ASMN1; SMN2HTTCYP1A2 | |
| SCHEMBL10549388 | 0.73 | HTR1A (0.47) | L3MBTL1RAB9AMAOBMAOASMN1; SMN2 | |
| SCHEMBL6568015 | 0.71 | MAPT (0.48) | RAB9AMAOBMAOASMN1; SMN2MAPT | |
| SCHEMBL8759753 | 0.71 | MAOB (0.56) | L3MBTL1RAB9AMAOBMAOAMAPT | |
| SCHEMBL7878656 | 0.71 | ALDH1A1 (0.53) | L3MBTL1RAB9ASMN1; SMN2MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0711288-A1 | PIPERAZINE DERIVATIVES AS ALPHA 1A-ADRENERGIC RECEPTOR ANTAGONISTS | RECORDATI INDUSTRIA CHIMICA E FARMACEUTICA S.p.a. (IT) | 1996-05-15 | — | — | EP | disclosed |
| WO-1995004049-A1 | PIPERAZINE DERIVATIVES AS α1A-ADRENERGIC RECEPTOR ANTAGONISTS | RECORDATI S.A., CHEMICAL AND PHARMACEUTICAL COMPANY (CH) | 1995-02-09 | — | — | WO | disclosed |