Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.34 |
| ▸ | GABRP | O00591 | 1/20 | 0.33 |
| ▸ | GABRD | O14764 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.33 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.33 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.33 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.33 |
| ▸ | GABRE | P78334 | 1/20 | 0.33 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.33 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.33 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.33 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.33 |
| ▸ | FBP1 | P09467 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985540 | 0.82 | PTGS2 (0.45) | PTGS1APPPTGS2FBP1LMNA | |
| SCHEMBL8985333 | 0.79 | GSK3B (0.42) | PTGS1APPPTGS2ALDH1A1SMN1; SMN2 | |
| SCHEMBL8985365 | 0.78 | PTGS1 (0.35) | PTGS1PTGS2LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL8985272 | 0.77 | MAPK14 (0.52) | PTGS1PTGS2FBP1LMNAALDH1A1 | |
| SCHEMBL8985463 | 0.77 | PTGS1 (0.35) | PTGS1PTGS2ALDH1A1NPC1L3MBTL1 | |
| SCHEMBL8985459 | 0.75 | CYP1A2 (0.37) | PTGS1PTGS2LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL3790289 | 0.72 | ALDH1A1 (0.58) | APPPTGS2LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL8985268 | 0.72 | MAPK14 (0.57) | PTGS1PTGS2LMNAALDH1A1SMN1; SMN2 | |
| SCHEMBL112595 | 0.70 | — | — | |
| SCHEMBL10844270 | 0.69 | OPRD1 (0.56) | APPPTGS2ALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5571810-A | ANTIINFLAMMATORY AGENTS, ANALGESICS, COLLAGEN DISEASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1996-11-05 | — | — | US | disclosed |