Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 5/20 | 0.68 |
| ▸ | MMP2 | P08253 | 4/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.56 |
| ▸ | RAB9A | P51151 | 4/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.56 |
| ▸ | HPGD | P15428 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.56 |
| ▸ | NPC1 | O15118 | 3/20 | 0.55 |
| ▸ | LMNA | P02545 | 2/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | ATM | Q13315 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | GLA | P06280 | 1/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | HTT | P42858 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | ROCK2 | O75116 | 2/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9688119 | 0.94 | MMP13 (0.61) | MMP13MMP2ALDH1A1RAB9AKDM4E | |
| SCHEMBL8985906 | 0.88 | SRD5A2 (0.60) | MMP13ALDH1A1RAB9AKDM4EHPGD | |
| SCHEMBL7833243 | 0.85 | LEF1 (0.55) | MMP13MMP2ALDH1A1RAB9AKDM4E | |
| SCHEMBL24601450 | 0.83 | MMP13 (0.72) | MMP13MMP2ALDH1A1RAB9AKDM4E | |
| SCHEMBL8209912 | 0.82 | MMP13 (0.83) | MMP13MMP2ALDH1A1RAB9AKDM4E | |
| SCHEMBL8204370 | 0.82 | MMP13 (0.83) | MMP13MMP2ALDH1A1RAB9AKDM4E | |
| SCHEMBL9687928 | 0.82 | MMP13 (0.46) | MMP13MMP2ALDH1A1RAB9AKDM4E | |
| SCHEMBL6512775 | 0.82 | HRH3 (0.71) | MMP13MMP2ALDH1A1RAB9AKDM4E | |
| SCHEMBL28230399 | 0.82 | MMP13 (0.70) | MMP13MMP2ALDH1A1RAB9AKDM4E | |
| SCHEMBL8209921 | 0.81 | MMP13 (0.81) | MMP13MMP2ALDH1A1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563142-A | INHIBITORS OF VIRAL REVERSE TRANSCRIPTASE | THE UPJOHN COMPANY (US) | 1996-10-08 | — | — | US | disclosed |
| EP-0507861-B1 | DIAROMATIC SUBSTITUTED ANTI-AIDS COMPOUNDS | UPJOHN CO (US) | 1996-09-11 | — | — | EP | disclosed |
| US-5489593-A | Anti-aids piperazines | THE UPJOHN COMPANY (US) | 1996-02-06 | — | — | US | disclosed |