Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP13 | P45452 | 5/20 | 0.61 |
| ▸ | MMP2 | P08253 | 4/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | RAB9A | P51151 | 4/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.50 |
| ▸ | HPGD | P15428 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 3/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | ATM | Q13315 | 2/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8985820 | 0.94 | MMP13 (0.68) | MMP13MMP2ALDH1A1RAB9AKDM4E | |
| SCHEMBL8985906 | 0.82 | SRD5A2 (0.60) | MMP13ALDH1A1RAB9AKDM4EHPGD | |
| SCHEMBL656018 | 0.81 | KDM4E (0.74) | MMP13MMP2ALDH1A1RAB9AKDM4E | |
| SCHEMBL7833243 | 0.80 | LEF1 (0.55) | MMP13MMP2ALDH1A1RAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL28674698 | 0.80 | KDM4E (0.72) | MMP13MMP2ALDH1A1RAB9AKDM4E | |
| SCHEMBL28292641 | 0.78 | MMP13 (0.66) | MMP13MMP2ALDH1A1RAB9AKDM4E | |
| SCHEMBL28292644 | 0.78 | MMP13 (0.66) | MMP13MMP2ALDH1A1RAB9AKDM4E | |
| SCHEMBL24601450 | 0.78 | MMP13 (0.72) | MMP13MMP2ALDH1A1RAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL23466639 | 0.78 | MMP13 (0.65) | MMP13MMP2ALDH1A1RAB9AKDM4E | |
| Hydrochloric Acid SCHEMBL23466637 | 0.78 | MMP13 (0.65) | MMP13MMP2ALDH1A1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0507861-A1 | DIAROMATIC SUBSTITUTED ANTI-AIDS COMPOUNDS. | UPJOHN CO (US) | 1992-10-14 | — | — | EP | disclosed |
| WO-1991009849-A1 | DIAROMATIC SUBSTITUTED ANTI-AIDS COMPOUNDS | THE UPJOHN COMPANY (US) | 1991-07-11 | — | — | WO | disclosed |