Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | XDH | P47989 | 1/20 | 0.48 |
| ▸ | CRHBP | P24387 | 3/20 | 0.46 |
| ▸ | CRHR2 | Q13324 | 3/20 | 0.46 |
| ▸ | AR | P10275 | 5/20 | 0.43 |
| ▸ | APP | P05067 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL899467 | 0.90 | ALDH1A1 (0.44) | MAPTCYP1A2CYP2C9ALDH1A1LMNA | |
| SCHEMBL899302 | 0.85 | CCNE1 (0.42) | ALDH1A1LMNAKDM4E | |
| SCHEMBL899084 | 0.82 | KCNH2 (0.38) | MAPTNPSR1ALDH1A1L3MBTL1LMNA | |
| SCHEMBL899508 | 0.82 | HDAC1 (0.47) | MAPTCYP3A4CYP2C9ALDH1A1MEN1 | |
| SCHEMBL903025 | 0.81 | HDAC1 (0.40) | CYP3A4ALDH1A1KDM4E | |
| SCHEMBL899366 | 0.79 | HSD17B2 (0.46) | APPLMNASMN1; SMN2MMP2MMP9 | |
| SCHEMBL902944 | 0.77 | HDAC1 (0.38) | ALDH1A1KDM4E | |
| SCHEMBL5843018 | 0.77 | CRHBP (0.64) | CRHBPCRHR2ARCYP1A2CYP2C9 | |
| SCHEMBL20379759 | 0.74 | XDH (0.76) | XDHAPPMAPTPOLBCYP3A4 | |
| SCHEMBL899484 | 0.73 | ALDH1A1 (0.38) | MAPTCYP1A2POLBCYP2C9ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012040754-A2 | NOVEL THIAZOLAMINE DERIVATES AS DIFFERENTIATION ACCELERATORS | TECHNISCHE UNIVERSITÄT WIEN (AT) | 2012-04-05 | — | — | WO | disclosed |
| WO-2012040754-A2 | NOVEL THIAZOLAMINE DERIVATES AS DIFFERENTIATION ACCELERATORS | TECHNISCHE UNIVERSITÄT WIEN (AT) | 2012-04-05 | — | — | WO | disclosed |