Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.36 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.32 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.31 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL692667 | 0.80 | MAPT (0.52) | KDM4EALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL8990040 | 0.80 | ALDH1A1 (0.43) | KDM4EALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL1266941 | 0.78 | ALKBH5 (0.49) | KDM4EALDH1A1MEN1KMT2A | |
| SCHEMBL10400766 | 0.78 | KDM4E (0.33) | KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL10995515 | 0.76 | ALDH1A1 (0.41) | ATAD2CECR2KDM4EALDH1A1MAPT | |
| SCHEMBL6053229 | 0.75 | KDM4E (0.30) | KDM4EALDH1A1MAPTSMN1; SMN2 | |
| SCHEMBL8990086 | 0.74 | ALDH1A1 (0.58) | KDM4EALDH1A1MAPTSMN1; SMN2MEN1 | |
| SCHEMBL11653654 | 0.74 | CASP6 (0.35) | ATAD2CECR2KDM4EALDH1A1MAPT | |
| SCHEMBL11496671 | 0.73 | ALKBH5 (0.40) | ATAD2CECR2KDM4EALDH1A1MAPT | |
| SCHEMBL9786518 | 0.72 | NOX4 (0.44) | KDM4EALDH1A1MAPTSMN1; SMN2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE35359-E | Amine salts of azo pigments based on pyrazolone derivatives | CIBA-GEIGY CORPORATION (US) | 1996-10-22 | — | — | US | disclosed |
| EP-0241413-B1 | AMINE SALTS OF AZO COMPOUNDS | CIBA-GEIGY AG (CH) | 1993-03-03 | — | — | EP | disclosed |
| US-5151505-A | Monoazo dyes containing hydroxypyrazole groups | CIBA-GEIGY CORPORATION (US) | 1992-09-29 | — | — | US | disclosed |
| US-4992495-A | Yellow pigment | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |
| US-4980458-A | Mixed sodium, ammonium and/or calcium salt crystals of laked monoazo disulfonated pyrazolone pigments | CIBA-GEIGY CORPORATION (US) | 1990-12-25 | — | — | US | disclosed |
| EP-0263074-A2 | Mixed crystals of laked azo dyes | CIBA-GEIGY AG (CH) | 1988-04-06 | — | — | EP | disclosed |
| EP-0241413-A2 | Amine salts of azo compounds | CIBA-GEIGY AG (CH) | 1987-10-14 | — | — | EP | disclosed |