Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GHSR | Q92847 | 4/20 | 0.48 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.36 |
| ▸ | PTGER1 | P34995 | 3/20 | 0.35 |
| ▸ | DRD2 | P14416 | 4/20 | 0.34 |
| ▸ | DRD4 | P21917 | 4/20 | 0.34 |
| ▸ | DRD3 | P35462 | 4/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 2/20 | 0.33 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.33 |
| ▸ | DRD1 | P21728 | 2/20 | 0.33 |
| ▸ | DRD5 | P21918 | 2/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.33 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.32 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8990880 | 0.92 | GHSR (0.42) | GHSRHDAC1PTGER1DRD2DRD4 | |
| SCHEMBL8990941 | 0.88 | GHSR (0.62) | GHSRHDAC1PTGER1DRD2DRD4 | |
| SCHEMBL8990988 | 0.86 | GHSR (0.38) | GHSRHDAC1PTGER1DRD2DRD4 | |
| SCHEMBL8990726 | 0.85 | GHSR (0.37) | GHSRHDAC1PTGER1DRD2DRD4 | |
| SCHEMBL8990905 | 0.84 | TSHR (0.37) | GHSRHDAC1SMN1; SMN2AGTR1MEN1 | |
| SCHEMBL8990776 | 0.83 | GHSR (0.47) | GHSRHDAC1PTGER1SMN1; SMN2AGTR1 | |
| SCHEMBL8990909 | 0.83 | GHSR (0.38) | GHSRHDAC1DRD2DRD4DRD3 | |
| SCHEMBL8990849 | 0.83 | GHSR (0.42) | GHSRHDAC1PTGER1SMN1; SMN2AGTR1 | |
| SCHEMBL8990845 | 0.82 | GHSR (0.37) | GHSRHDAC1PTGER1DRD2DRD4 | |
| SCHEMBL8991006 | 0.82 | GHSR (0.37) | GHSRHDAC1DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | claimed |
| US-5545735-A | ANIMAL GROWTH REGULATORS | MERCK & CO., INC. (US) | 1996-08-13 | — | — | US | disclosed |