Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 3/20 | 0.37 |
| ▸ | CES1 | P23141 | 3/20 | 0.37 |
| ▸ | LTA4H | P09960 | 2/20 | 0.35 |
| ▸ | PCSK9 | Q8NBP7 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | NAAA | Q02083 | 2/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL417994 | 0.91 | LTA4H (0.38) | CES2CES1LTA4HPCSK9PTGS2 | |
| SCHEMBL29847552 | 0.86 | TP53 (0.35) | CES2CES1SIGMAR1 | |
| SCHEMBL418321 | 0.84 | LTA4H (0.38) | CES2CES1LTA4HPCSK9SMN1; SMN2 | |
| SCHEMBL12816111 | 0.83 | LTA4H (0.33) | CES2CES1LTA4HPCSK9PTGS2 | |
| SCHEMBL415280 | 0.83 | DNM1 (0.40) | CES2CES1NAAASMN1; SMN2SIGMAR1 | |
| SCHEMBL418038 | 0.83 | DNM1 (0.40) | CES2CES1NAAASMN1; SMN2SIGMAR1 | |
| SCHEMBL9643720 | 0.83 | DNM1 (0.40) | CES2CES1NAAASMN1; SMN2SIGMAR1 | |
| SCHEMBL8992386 | 0.83 | DNM1 (0.40) | CES2CES1NAAASMN1; SMN2SIGMAR1 | |
| SCHEMBL9745925 | 0.82 | PTPN1 (0.34) | CES2CES1LTA4HPCSK9PTGS2 | |
| SCHEMBL80927 | 0.81 | TP53 (0.41) | CES2CES1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5516871-A | Diphenylsiloxane oligomers functionalized at both terminals and methods for the preparation thereof | DOW CORNING ASIA, LTD. (JP) | 1996-05-14 | — | — | US | claimed |
| US-5502229-A | ENDCAPPING | DOW CORNING ASIA, LTD. (JP) | 1996-03-26 | — | — | US | claimed |
| US-5516871-A | Diphenylsiloxane oligomers functionalized at both terminals and methods for the preparation thereof | DOW CORNING ASIA, LTD. (JP) | 1996-05-14 | — | — | US | disclosed |
| US-5502229-A | ENDCAPPING | DOW CORNING ASIA, LTD. (JP) | 1996-03-26 | — | — | US | disclosed |